Visual Analysis of Animal Experiments on Traditional Chinese Medicine (TCM) Nursing Technology Based on VOSviewer

doi:10.12300/j.issn.1674-5817.2023.037

Abstract

Abstract:

Objective Through the visual analysis of animal experimental literature on Traditional Chinese Medicine (TCM) nursing technology, the relevant research hot spots were condensed and the research trends of relevant animal models were discussed, to provide reference for subsequent research. Methods The literature related to animal experiments on Chinese medicine nursing technology was retrieved from Wan Fang database, Chinese Science and Technology Journal Database (VIP), China National Knowledge Infrastructure Engineering Database (CNKI), China Biomedical Literature Database (CBM), PubMed and Web of Science until June 30, 2022. Visual analysis was performed using VOSviewer 1.6.17 software. Results A total of 1 864 articles in Chinese and 126 articles in English were included, with the number of annual publications increasing year by year. The relevant literature involved 18 TCM nursing techniques, with the largest number (426) involving massage having the highest number of articles. It involved 4 496 authors, out of whom 358 were core authors accounting for 7.9% of all authors, and had a total count of 3 706 keywords forming 7 clusters. The research hotspots mainly included massage treatment of inflammatory diseases and analgesic effect, acupoint injection treatment of allergic rhinitis and myocardial ischemia, acupoint application treatment of asthma-related respiratory diseases, and moxibustion treatment of inflammatory diseases. The study of the mechanism of abdominal massage on insulin resistance is the latest research topic among them. Conclusion In recent years, the animal model of abdominal massage has gained increasing popularity in animal experiments of TCM nursing techniques. However, the establishment and application of animal models related to Chinese medicine soaking and Chinese medicine hot ironing have not yet received attention. This area can be explored in the future to further improve the animal experimental research on Chinese medicine nursing technology.

Key words: VOSviewer, Traditional Chinese medicine nursing technology, Animal experiment, Visual analysis

CLC Number:

R-332

Jinhuan MIAO, Xia XU, Lu ZHOU, Haiyan CHENG, Yan HE. Visual Analysis of Animal Experiments on Traditional Chinese Medicine (TCM) Nursing Technology Based on VOSviewer[J]. Laboratory Animal and Comparative Medicine, 2023, 43(6): 626-635.

Figures/Tables 5

Figure 1 Trend chart (A), quantity ranking (B) and author cooperation status (C) of animal experiments related to medical and nursing technologyNote：A, Trend chart of literature publication in the TCM nursing technology animal experiment (The blue data line indicates the number of annual publications, and the orange line indicates the overall trend of publications). B, Ranking of animal experimental literature on 18 TCM nursing techniques. C, Author cooperation network diagram (Nodes represent the author; The line indicates the cooperation between authors. The closer the distance, the more frequent the cooperation between authors. The same color represents the same cluster).

Table 1 High-frequency keywords

序号 Serial number	关键词 Keyword	频次 Frequency	共现次数 Number of co-occurrences
1	大鼠	184	219
2	穴位注射	182	155
3	推拿	129	104
4	艾灸	111	93
5	溃疡性结肠炎	104	85
6	麦粒灸	67	41
7	实验研究	55	68
8	动物模型	54	42
9	穴位敷贴	53	43
10	动物实验	47	49
11	足三里	40	54
12	类风湿性关节炎	40	45
13	推拿手法	40	22
14	灸法	37	58
15	哮喘	37	32

Figure 2 Co-occurrence label view（A）， density view（B） and time trend diagram （C） of the keywordsNote：A is keyword co-occurrence tag view (each node represents a keyword, with node size indicating frequency; nodes of the same color belong to the same cluster; thicker lines indicate closer connections between keywords). B is the keyword density view (the closer the color is to yellow in the figure, the higher the keyword density and the higher the frequency of occurrence). C is time trend diagram of keywords (nodes represent keywords; the color from blue to yellow indicates the time from far to near).

Table 2 Keyword clustering and research topics in the animal experimental literature of TCM nursing technology

聚类ID Cluster ID	关键词数量 Number of keywords	研究主题 Research topic	主要关键词 Main keywords
#1红色 #1 Red	13	推拿治疗炎症性疾病及镇痛效应	动物模型、坐骨神经损伤、实验研究、家兔、按摩、推拿、推拿手法、类风湿关节炎、类风湿性关节炎、艾灸、血液流变学、镇痛、骨骼肌
#2绿色 #2 Green	12	灸法治疗炎性疾病	关节炎、动物、大鼠、小鼠、灸法、电针、疾病模型、穴、结肠炎、足三里、针灸疗法、间接灸
#3深蓝色 #3 Dark blue	9	穴位敷贴治疗哮喘相关呼吸道疾病	中药、动物实验、哮喘、支气管哮喘、穴位敷贴、穴位贴敷、细胞因子、行为学、豚鼠
#4浅黄色 #4 Light yellow	8	穴位注射治疗变应性鼻炎、心肌缺血，隔药灸治疗原发性痛经的疗效	临床疗效、原发性痛经、变应性鼻炎、心肌缺血、穴位注射、细胞凋亡、隔药灸、TNF-α
#5紫色 #5Purple	6	推拿治疗炎性疾病	免疫功能、推拿疗法、溃疡性结肠炎、疗效评价、肿瘤坏死因子-α、腹部推拿
#6浅蓝色 #6 Baby blue	6	机制研究	D－半乳糖、一氧化氮、丙二醛、学习记忆、超氧化物歧化酶、黄芪注射液
#7姜黄色 #7 Ginger	5	灸法治疗高脂血症	兔、环磷酰胺、隔药饼灸、高脂血症、麦粒灸

Figure 3 Tag view with keyword massage (A) and visuali diagram of time overlay of keywords in literature of massage animal tests (B)Note： In figure A， node represents keyword， node size represents keyword frequency， the same color represents the same cluster； The thicker the line， the closer the distance， the closer the keyword connection. The purple category marked in the figure indicates the clustering of key words in animal experiments of abdominal massage. In figure B， nodes represent keywords， the color from blue to yellow indicates the time from far to near. The yellow highlighted part of the figure indicates that the mechanism of insulin resistance is the subject of recent research in animal experiments on abdominal massage.

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