Analysis on Pathogen Infection of Mice and Rats in Shanghai from 2010 to 2013

doi:10.3969/j.issn.1674-5817.2015.05.011

Abstract

Abstract: Objective To investigate the pathogen infection status of laboratory mice and rats in Shanghai. Methods The quality monitoring for viruses, bacteria and parasites in SPF or clean rats and mice was conducted according to national standards, in which the method, equipment and reagents were referring to the requirements of national standards. Results From 2010 to 2013 in Shanghai, the mainly identified pathogens infecting the mice and rats included the Staphylococcus aureus, Pseudomonas aeruginosa, Mycoplasma and Tyzzer's organism. And the mainly identified viruses infecting the mice and rats were mouse hepatitis virus and Sendai virus etc. Meanwhile, the mainly identified parasites were all Helminths, Flagellates and Ectoparasites. During this period, the detection rate of Staphylococcus aureus presented the downtrend in mice, but the detection rate of Tyzzer's organism and Mycoplasma showed uptrend. In addition, the detection rate of Tyzzer's organism, Sendai virus and all Helminths in rats increased year by year during this period. Conclusion In Shanghai region the quality of laboratory mice and rats needs to be improved. And the regulatory authorities in laboratory animal should strengthen the administration and quality monitoring of the rats and mice in the Shanghai.

Key words: Laboratory animal, Pathogen detection, Infection rate

CLC Number:

Q95-33

FENG Li-ping, TAO Ling-yun, FENG Jie, XIE Jian-yun, LIN Jin-xing, WANG Sheng-chang, ZHOU Jie, WEI Xiao-feng, GAO Cheng, XING Zheng-hong. Analysis on Pathogen Infection of Mice and Rats in Shanghai from 2010 to 2013[J]. Laboratory Animal and Comparative Medicine, 2015, 35(5): 398-402.

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