Abstract: Objective To explore the effects of problem-based learning (PBL) with case-based teaching in experiment of laboratory animal science. Methods Sixty experiment objects randomly selected every year from junior college students during 2012-2014 were divided into two groups. In class A, lecture-based learning (LBL) teaching mode was used. In class B PBL with case-based teaching mode was used. And then the teaching effect was evaluated by means of the questionnaire survey and experiment report grading. Results The students of class B were superior to that of class A on how to design the animal experiment, experimental animal ethics practical applications, analytical ability of animal experiment results, animal experiment report writing, who showed good teaching effect. Conclusion The application of PBL with case-based teaching mode in laboratory animal science experiment could increase their learning enthusiasm by stimulating interests of students and improvement of the quality of experimental teaching.

Key words: Problem-based learning (PBL), Case-based teaching, Teaching mode, Laboratory animal science, Experiment