Laboratory Animal and Comparative Medicine ›› 2020, Vol. 40 ›› Issue (1): 70-73.DOI: 10.3969/j.issn.1674-5817.2020.01.012

Special Issue: 实验动物管理 实验动物设施设备

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Application of Sentinel Animals in Barrier Environment

ZHAO Yong, FAN Chun, ZHU Minjuan, JIN Yi, CHEN Guoqiang   

  1. Shanghai Laboratory Animal Research Center, Shanghai 201203 China
  • Received:2019-04-18 Online:2020-02-25 Published:2020-12-18

Abstract: Sentinel animals in barrier environment should not only take into account the species, strain, sex, age, quantity, contact mode, placement position and detection frequency, but also the elimination of interference of animal stress on the monitoring results. Aaccording to the 3R theory of laboratory animals, make full use of sentinel animals as feed nutrition monitoring sentinel animals, put forward to set up the number of sentinel animals, that is the actual detection number of sentinel animals.

Key words: Sentinel animal, Feed nutrition monitoring, Laboratory animal, 3R

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