Application Prospect of Identification and Traceability Technology of Laboratory Animals in Biosafety Laboratory

doi:10.12300/j.issn.1674-5817.2021.174

Abstract

Abstract:

Effective management of laboratory biosafety plays one of the most important roles in the national biosafety system. Laboratory animals have been widely used in the life science research field, including infection animal experiments, which have to be done in the animal biosafety laboratory (ABSL). The risk assessment and control related to laboratory animals and animal experiments are the most important affairs in ABSL, and the identification and traceability of laboratory animals detected by wireless tracking technology represent a developing tendency in ABSL management. From the perspective of biosafety, this paper summarized the development of laboratory animal identification and traceability technology,and described the application prospect in ABSL management of non-contact identification technology, especially radio frequency identification technology, which can provide reference for relevant practitioners to use the identification and traceability technology of experimental animals for biosafety control.

Key words: Biosafety, Experimental animals, Traceability technology, Identification

CLC Number:

Q95-33

Lixiang CHEN, Boyin QIN, Hua YANG, Chunhua XU, Xiuhua PENG, Shun LI, Xiaohui ZHOU. Application Prospect of Identification and Traceability Technology of Laboratory Animals in Biosafety Laboratory[J]. Laboratory Animal and Comparative Medicine, 2022, 42(2): 89-94.

References 32

1	史光华, 张晓迪, 吕龙宝, 等. 实验动物机构标记系统的比较研究[J]. 实验动物科学, 2017, 34(3):55-60, 65. DOI:10.3969/j.issn.1006-6179.2017.03.012 .
2	«中华人民共和国生物安全法»摘录: 病原微生物实验室生物安全[J]. 实验动物与比较医学, 2021, 41(5):465.
3	DAHLBORN K, BUGNON P, NEVALAINEN T, et al. Report of the Federation of European Laboratory Animal Science Associations Working Group on animal identification[J]. Lab Anim, 2013, 47(1):2-11. DOI:10.1177/002367712473290 .
4	KUMAR P, REINITZ H W, SIMUNOVIC J, et al. Overview of RFID technology and its applications in the food industry[J]. J Food Sci, 2009, 74(8): R101-R106. DOI:10.1111/j.1750-3841. 2009.01323.x .
5	CUI L, ZHANG Z H, GAO N, et al. Radio frequency identification and sensing techniques and their applications:A review of the state-of-the-art[J]. Sensors (Basel), 2019, 19(18):4012. DOI:10.3390/s19184012 .
6	周永运, 王荣, 翟培军, 等. 实验动物与生物安全研究进展[J]. 畜牧兽医科技信息, 2015(12):4-6. DOI:10.3969/J.ISSN.1671-6027.2015.12.001 .
7	李俊勇, 赵文红, 杨智明. 吸取SARS实验室感染教训预防鼠疫实验室感染发生[J]. 医学动物防制, 2006(2):85-86.DOI:10.3969/j.issn.1003-6245.2006.02.003 .
8	刘静, 李超, 柳金雄, 等. 高等级生物安全实验室在生物安全领域的作用及其发展的思考 [J]. 中国农业科学, 2020, 053(001): 74-80.DOI:10.3864/j.issn.0578-1752.2020.01.007 .
9	陆兵, 李京京, 程洪亮, 等. 我国生物安全实验室建设和管理现状 [J]. 实验室研究与探索,2012,031(001):192-196. DOI:10.3969/j.issn.1006-7167.2012.01.055 .
10	王君玮. 我国实验室生物安全发展现状与趋势[J]. 中国家禽, 2010, 32(14):1-4, 8. DOI:10.16372/j.issn.1004-6364.2010.14.001 .
11	白殿卿. 实验猴身份自动识别、自动捕捉、电子芯片数据信息管理系统的研制[J]. 中国比较医学杂志, 2011, 21(7):50-54. DOI:10.3969/j.issn.1671.7856.2011.07.011 .
12	薛康宁, 李晓燕, 荣蓉, 等. 动物生物安全二级实验室实验活动管理要点探讨[J]. 实验动物科学, 2014, 31(5):42-45. DOI:10.3969/j.issn.1006-6179.2014.05.010 .
13	MCCORMICK-ELL J, CONNELL N. Laboratory safety, biosecurity, and responsible animal use[J]. ILAR J, 2019, 60(1):24-33. DOI:10.1093/ilar/ilz012 .
14	BLANCHARD K T, BARTHEL C, FRENCH J E, et al. Transponder-induced sarcoma in the heterozygous p53^+/- mouse[J]. Toxicol Pathol, 1999, 27(5):519-527. DOI:10.1177/019262339902700505 .
15	易爱华, 赵晓宏, 康卫勇, 等. 条码技术发展现状及其在环保领域的应用探索[J]. 环境与可持续发展, 2014, 39(6):107-111. DOI:10.19758/j.cnki.issn1673-288x.2014.06.028 .
16	曹闯乐, 于洪涛. 无线射频识别技术在物联网方向的应用[J]. 科学技术创新, 2020(22):107-108. DOI:10.3969/j.issn.1673-1328. 2020.22.064 .
17	VOULODIMOS A S, PATRIKAKIS C Z, SIDERIDIS A B, et al. A complete farm management system based on animal identification using RFID technology[J]. Comput Electron Agric, 2010, 70(2):380-388. DOI:10.1016/j.compag.2009.07.009 .
18	GRUDA M C, PINTO A, CRAELIUS A, et al. A system for implanting laboratory mice with light-activated microtrans-ponders[J]. J Am Assoc Lab Anim Sci, 2010, 49(6):826-831. DOI:10.1093/mollus/eyq030 .
19	ISERBYT A, GRIFFIOEN M, BORREMANS B, et al. How to quantify animal activity from radio-frequency identification (RFID) recordings[J]. Ecol Evol, 2018, 8(20):10166-10174. DOI:10.1002/ece3.4491 .
20	刘雄伟, 沈志敏, 魏晓锋, 等. 小鼠植入RFID芯片生理生化值的测定[J]. 实验动物与比较医学, 2012, 32(3):238-240. DOI:10.3969/j.issn.1674-5817.2012.03.014 .
21	陈懿斐, 魏晓锋, 高诚, 等. RFID技术在实验动物行业中的应用的探讨[J]. 实验动物与比较医学, 2016, 36(1):51-53, 56. DOI:10.3969/j.issn.1674-5817.2016.01.010 .
22	黄孟选, 李丽华, 许利军, 等. RFID技术在动物个体行为识别中的应用进展[J]. 中国家禽, 2018, 40(22):39-44. DOI:10.16372/j.issn.1004-6364.2018.22.009 .
23	ZELDOVICH L. RFID: untangling mutant phenotypes[J]. Lab Anim, 2016, 45(11):427-430. DOI:10.1038/laban.1146 .
24	BAINS R S, CATER H L, SILLITO R R, et al. Analysis of individual mouse activity in group housed animals of different inbred strains using a novel automated home cage analysis system[J]. Front Behav Neurosci, 2016, 10:106. DOI:10.3389/fnbeh.2016.00106 .
25	NOORSHAMS O, BOYD J D, MURPHY T H. Automating mouse weighing in group homecages with Raspberry Pi micro-computers[J]. J Neurosci Methods, 2017, 285:1-5. DOI:10.1016/j.jneumeth.2017.05.002 .
26	伏仕波, 肖宛昂, 毛文宇, 等. 一种面向植入式RFID标签的温度传感器[J]. 微电子学, 2019, 49(6):772-776, 782. DOI:10.13911/j.cnki.1004-3365.190064 .
27	PELEH T, BAI X S, KAS M J H, et al. RFID-supported video tracking for automated analysis of social behaviour in groups of mice[J]. J Neurosci Methods, 2019, 325:108323. DOI:10.1016/j.jneumeth.2019.108323 .
28	刘秀敏, 魏冬霞. RFID技术在畜牧业中的应用探析[J]. 家畜生态学报, 2020, 41(1):78-80. DOI:10.3969/j.issn.1673-1182. 2020.01.016 .
29	ROJO-MOLINERO E, ALADOS J C, DE LA PEDROSA E G G, et al. Safety in the microbiology laboratory[J]. Enferm Infecc Microbiol Clin, 2015, 33(6):404-410. DOI:10.1016/j.eimc. 2014.06.014 .
30	胡凯, 马宏, 贾松树, 等. 实验室生物安全风险评估的现状与思考[J]. 医学动物防制, 2020, 36(9):817-820. DOI:10.7629/yxdwfz 202009001 .
31	周淑佩, 田枫, 贾光. 实验动物从业人员的职业安全及个人防护[J]. 实验动物科学, 2013, 30(1):50-54. DOI:10.3969/j.issn.1006-6179.2013.01.014 .
32	GUO S T, XU P F, MIAO Q G, et al. Automatic identification of individual Primates with deep learning techniques[J]. iScience, 2020, 23(8):101412. DOI:10.1016/j.isci.2020.101412 .

[1]	Xiaoyu LIU, Xuancheng LU, Xiaomeng SHI, Yuzhou ZHANG, Chao LÜ, Guoyuan CHEN, Xiao LU, Yu BAI, Jing GAO, Yao LI, Yonggang LIU, Yufeng TAO, Wanyong PANG. Explanation and Elaboration for the ARRIVE Guidelines 2.0—Reporting Animal Research and In Vivo Experiments (Ⅲ) [J]. Laboratory Animal and Comparative Medicine, 2023, 43(4): 446-456.
[2]	Shibo SU, Wenjie MA, Wei WANG, Huijuan GUO, He ZHANG, Zi WANG, Lei KANG, Shouqi LIU, Huairan LIU, Changde SI, Chuntian GOU, Wei ZHANG, Hongyan CHEN. Performance Test and Evaluation of Self-developed Biosafety Cage Changing Workbench [J]. Laboratory Animal and Comparative Medicine, 2022, 42(2): 102-110.
[3]	Wenjie MA, Wei ZHANG, Wei WANG, Shibo SU, Huijuan GUO, He ZHANG, Zi WANG, Huairan LIU, Hongyan CHEN. Performance Analysis of Class Ⅱ Biosafety Cabinetry in Veterinary-related Research Institutes [J]. Laboratory Animal and Comparative Medicine, 2022, 42(2): 111-116.
[4]	Yong LI, Liang ZHOU, Yong HE, Zhifeng YAN, Haijiang WANG. Preliminary Exploration of Information Supervison System for Harmless Disposal of Laboratory Animal Carcasses and Related Wastes [J]. Laboratory Animal and Comparative Medicine, 2022, 42(2): 122-126.
[5]	Yuqin YANG. Biosafety Problems and Countermeasures in the Management of Barrier Facilities for Laboratory Animals [J]. Laboratory Animal and Comparative Medicine, 2022, 42(2): 95-101.
[6]	CHEN Xiaojuan, LI Wei, WANG Lie. Exploration on Informatization of Laboratory Animal Management Process in Colleges and Universities: The Case of Zhejiang University [J]. Laboratory Animal and Comparative Medicine, 2021, 41(6): 554-558.
[7]	LUO Yinzhu, Min Fangui, WANG Jing, HE Lifang, PAN Jinchun. Prevention and Control of Pathogenic Microorganisms for the Management and Biosafety Control in Laboratory Animal Facilities [J]. Laboratory Animal and Comparative Medicine, 2021, 41(5): 443-449.
[8]	YANG Hua, ZHAO Yong, SONG Zhigang, LI Shun, ZHOU Xiaohui. A Brief Introduction About Key Points of Management in ABSL-2 Laboratory [J]. Laboratory Animal and Comparative Medicine, 2020, 40(2): 149-153.
[9]	ZHENG Mao-en, YANG Chun-hong, WANG Ke-zhou, LIU Tao, ZHAO Yuan-dong. Research Progress on Occupational Allergy of Laboratory Animal [J]. Laboratory Animal and Comparative Medicine, 2019, 39(5): 418-422.
[10]	WANG Xuan, WANG Wen-guang, LI Na, YUAN Yuan, ZHANG Zhi-cheng, SUN Xiao-mei. Isolation and Identification of Spinal Astrocytes from Tree Shrews [J]. Laboratory Animal and Comparative Medicine, 2019, 39(1): 15-20.
[11]	XU Qing-hua, TONG Lin. Application of Analytic Hierarchy Process in Biosafety Management of Laboratory Animals [J]. Laboratory Animal and Comparative Medicine, 2018, 38(4): 299-303.
[12]	ZHAO Wei-bo, MIN Fan-gui, PAN Jin-chun, MEI Yi-duo, HUANG Hai-yan, HUANG Ren. Investigation on Several Heavy Metals and Harmful Chemicals in Different Beddings [J]. Laboratory Animal and Comparative Medicine, 2018, 38(4): 304-306.
[13]	XU Li-jing, SUN Chang, LU Tao-feng, CHEN Hong-yan, ZHAO Li-li. Application of PCR Method for Rapid Sex Determination in SPF Jinding Duck [J]. Laboratory Animal and Comparative Medicine, 2017, 37(3): 249-251.
[14]	XU Chun-hua, CHEN Li-xiang, REN Xiao-nan, YANG Yu-qin, PENG Xiu-hua, CAI Jia-lin, ZHOU Xiao-hui, ZHOU Wen-jiang. Application of PCR and Restiction Enzyme in Genotype Identification of uPA-SCID Mouse [J]. Laboratory Animal and Comparative Medicine, 2015, 35(3): 218-221.
[15]	GUO Xiao-ping, CHEN Shi-jin, LAN Gan-qiu, JIANG Qin-yang, GUO Ya-fen. Cloning and Identifying Expression Vectors of α-1,3 Galactosyltransferase Gene from Bama Minipig in Guangxi [J]. Laboratory Animal and Comparative Medicine, 2012, 32(1): 1-7.