Abstract:

Objective To study the anesthetic effects of Zoletil and Xylazine combined anesthesia on Bama mini-pig, and to observe the effect of combined anesthesia on the physiological indexes of Bama mini-pigs. Methods Thirty-two Bama mini-pigs undergoing surgical abdominal surgery were anesthetized by injecting Xylazine (2 mg/kg) combined with different doses of Zoletil (3.0-7.0 mg/kg) into the muscles behind the neck. The effective time of anesthesia, anesthesia maintenance time, and recovery time were recorded. Body temperature, respiration, heart rate, and other physiological indicators were monitored during anesthesia. Results The success rate of induction anesthesia at 3.0-3.9 mg/kg and 4.0-7.0 mg/kg of Zoletil was 50% and 100%, respectively. When the dosage of Zoletil was 4.0-7.0 mg/kg, the induction anesthesia time was shorter, the anesthesia maintenance time was longer, and there was no effect on the recovery time. When the dose of Zoletil was 5.0-5.9 mg/kg, the physiological indicators were close to the normal range. Conclusion The dosage of 5.0-5.9 mg/kg Zoletil combined with 2 mg/kg Xylazine had a positive effect on Bama mini-pigs as the vital signs remained stable during operation.

Key words: Bama mini-pigs, Zoletil, Xylazine, Anesthetic