基于Matlab的中枢缺氧反应的计算机仿真

›› 2006, Vol. 26 ›› Issue (2): 91-93.

基于Matlab的中枢缺氧反应的计算机仿真

1.苏州大学医学院生理学教研室,苏州 215123；2.苏州大学医学院神经细胞生物学研究室,苏州 215123

收稿日期:2006-03-09 出版日期:2006-06-25 发布日期:2006-06-25
基金资助:
苏州大学医学发展基金(EE134521)

Hypoxic Response of Central Nervous System Simulation Based on Matlab

1.Department of Physiology, Medical School, Soochow University, Suzhou，215123, China 2.Dept.of Neurocytobiology, Medical School, Soochow University, Suzhou, 215123, China

Received:2006-03-09 Online:2006-06-25 Published:2006-06-25

摘要/Abstract

摘要： 目的建立中枢缺氧反应的计算机仿真模型，评价它对心血管系统的作用。方法利用Matlab/Simulink仿真工具建立血流动力学模型，模型包括心脏、体循环和肺循环，并整合中枢缺氧反应。结果去除中枢缺氧反应的调节机制以后，心率增加的幅度减小，内脏动脉阻力变化的幅度却增大，提示中枢缺氧反应对心血管系统的稳态有着重要的调节作用。结论仿真结果有助于设计更好的动物实验。

关键词: 中枢缺氧反应, 数字仿真, Matlab

Abstract: Objective A mathematical model for hypoxic response of the central nervous is presented Method The model is built on Matlab/Simulink system. It combines the models of heart,systemic and pulmonary circulation systems together. The model is composed of carotid sinus baroreceptor afferent path,synpathetic nerve together with hypoxic response of the central nervous system and reflex effector. Results The simulation experiments showed that hypoxic response of the central nervous system plays an inportant part in cardiovascular system. Conclusion The（feveloped model was an effective means to simulate the kinetics of hypoxia.

Key words: Hypoxic response, Digital simulation, Matlab

周希平1, 孙茂民2. 基于Matlab的中枢缺氧反应的计算机仿真[J]. , 2006, 26(2): 91-93.

ZHOU Xi-Ping-1, SUN Mao-Min-2. Hypoxic Response of Central Nervous System Simulation Based on Matlab[J]. , 2006, 26(2): 91-93.