›› 2003, Vol. 23 ›› Issue (1): 12-14.

• 论文 • 上一篇    下一篇

猕猴肾脏自发病变的组织学观察

  

  1. 广东省实验动物监测所,广州 510260
  • 收稿日期:2002-07-04 出版日期:2003-01-25 发布日期:2013-03-19
  • 基金资助:

    国家“九五”重点科技项目(96-A-23-06-06) 广东省重点科技攻关项目(1998年第12批52号)

Histopathological Observation on Spontaneous Kidney Lesions in Macaca mulatta

  1. Guangdong Laboratory Animal Monitoring Institute,GuangZhou 510260, China
  • Received:2002-07-04 Online:2003-01-25 Published:2013-03-19

摘要: 为了解人工饲养条件下猕猴脏器自发病变的发生情况,建立猕猴自发病变的病理图谱。采用常规组织学技术,观察了各个年龄阶段的68例猕猴肾脏的组织病理变化。结果发现,79.4%的肾脏存在不同程度的病变,包括肾小球、肾小管和肾间质的多种病变共14种。肾组织病变程度和病变发生率随年龄增长增加。自发病变对动物实验的干扰应引起足够重视。

关键词: 猕猴, 肾, 病理学

Abstract: To study the histopathological changes in spontaneous kidney lesions of breeding maca-ca mulatta,kidney samples from the monkey at the age of 2~20 years were investigated by routine histological technique.The results showed that various spontaneous lesions including glomerulus’s,renal tubules and interrenal tissue etc, totaling more than 14 kinds in different degrees ,were found in 79. 4% of the monkeys. The degree and the frequency of the lesions were increased with age. The results suggested that the spontaneous lesions of kidney were often ob-served in macaca mulatta and its interference effect on medicine research should be considered se-riously.

Key words: Macaca mulatta, Kidney, Pathology