Research Progress of Tyzzer’s Organism in Quality Control of Laboratory Animals

doi:10.12300/j.issn.1674-5817.2021.166

Abstract

Abstract:

Tyzzer's organism is a kind of Clostridium piliforme, formerly Bacillus piliformis, which can cause hepatointestinal necrosis and diarrhea in animals. Tyzzer's disease caused by this pathogen is an acute disease with rapid onset, high mortality and no obvious clinical symptoms, so it is difficult to make early diagnosis and treatment. Once the outbreak, it will cause irreparable economic losses and laboratory safety problems. This article reviewed the biological characteristics, epidemiological and disease characteristics, detection methods, research progress of Tyzzer's organism, as well as the prevention and treatment of Tyzzer's organism.

Key words: Tyzzer organism, Tyzzer disease, Research progress, Prevention and treatment

CLC Number:

Q95-33

Junhao TAO, Huiqiong YAN, Hui XIE, Huazhong YING, Fangwei DAI. Research Progress of Tyzzer’s Organism in Quality Control of Laboratory Animals[J]. Laboratory Animal and Comparative Medicine, 2022, 42(4): 358-363.

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