Abstract: Objective To explore the effect of tooth grinding stone in mice and rats breeding. Methods Thirty C57BL/6 mice and 30 SD rats were randomly divided into 2 groups respectively at the age of 3 weeks. Group 1 was as control, and group 2 was given tooth grinding stone in cages, with 3 animals in one cage. All animals had free access to water and everyday weighed feed, the feed consumption were monitored. All animals were tested by open field test 3 months later. Results The feed consumption of group 1 was higher than group 2. Animals in group 2 like playing with the tooth grinding stone. Open field test show that there was no difference between group 1 and group 2 in the activity factor and emotionality factor. Conclusion Tooth grinding stone could save feed and make the life of animals colorful.

Key words: Grinding stones, Feed, Consumption, Activity, Animal welfare