Influence of Electromagnetic Radiation on Rats Liver under Complex Electromagnetic Environment

doi:10.3969/j.issn.1674-5817.2018.01.007

Abstract

Abstract: Objective To investigate the influence of electromagnetic radiation on rat’s health under the complex electromagnetic environment.Methods The Wistar rats were divided into control and treatment groups 1,2,3,and 4.Then they were exposed in complex electromagnetic environments for different certain period per day.After 30 days exposing,the livers of all rats were sampled and studied.Results Compared with the control group,liver cells of experimental rats were confirmed to be occurring apoptosis at both the DNA level and protein level.And the degree of apoptosis was increased with the exposure time.Conclusion Complex electromagnetic environment can damage rat health.

Key words: Electromagnetic environment, Electromagnetic radiation, Liver cells, Apoptosis

CLC Number:

Q95-33

LV Zhao-hui, ZHANG Wen-luan, GENG De-jun, FAN Yu-lin, SHENG Xiao-juan, LI Xi-ping. Influence of Electromagnetic Radiation on Rats Liver under Complex Electromagnetic Environment[J]. Laboratory Animal and Comparative Medicine, 2018, 38(1): 40-43.

References

[1] 钟秀宏,徐俊杰,刘洪梅,等.高功率微波辐射致大鼠心和肝损伤形态学观察[J].中国公共卫生,2010,26(12):1559-1560.
[2] 马惠荣,李媛媛,栗晶晶,等.900 MHz 拟手机电磁辐射对大鼠肝功能和肝细胞 Bax及 Bcl- 2 蛋白表达的影响[J].解放军医药杂志,2013,25(10):36-44
[3] Poulletier de Gannes F,Billaudel B,Haro E,et al.Rat fertility and embryo fetal development:influence of exposure to the Wi-Fi signal[J].Reprod Toxicol,2013,36(4):1-5.
[4] 王晓玲,赵舒武,王媛媛,等.当归补血汤对骨髓辐射损伤过程中NF-κB 及bax、bcl-2 表达的影响[J].中国老年学杂志,2015,35(6):2887-2890.
[5] 龚茜芬,杨学森,涂灵,等.复方中药制剂对电磁辐射致大鼠海马神经损伤的防治作用[J].中国应用生理学杂志,2013,29(4):346-350.
[6] 刘浩,陈卫刚,郑勇.硫氢化钠对肝硬化大鼠肝细胞凋亡及肝组织Bax、Bcl-2表达的影响[J].山东医药,2016,56(44):38-40.
[7] 刘凯军.手机电磁辐射对精液质量的影响及其生物学机制研究[D].重庆:第三军医大学,2016.
[8] 冯一中,莫亚虹.Bax蛋白在高能电子线大鼠皮肤辐射损伤模型中的表达及意义[J].苏州大学学报:医学版,2002:22(2):133-143.
[9] 甘晓,张东波,刘向业,等.脉冲磁场对颅脑损伤组织中内源性神经干细胞因子的影响[J].中国组织工程研究,2017,28(21):3376-3381.
[10] 何楚琦,王月,龙鼎新.电磁辐射对中枢神经系统的影响及机制[J].中国辐射卫生,2017,26(3):381-384.
[11] 张静,张博,王惠,等.长期微博辐射致大鼠心脏损伤远后效应的定量研究[J].中国体视学与图像分析,2017,L2(1):1-9.
[12] 崔亮,左红艳,王德文,等.微波辐射致大鼠海马损伤的磁共振影像学特征与其生物效应间关联性研究[J].中国体视学与图像分析,2017,22(1):77-86.

[1]	LI Hongbo, HUANG Rui, DAI Jiang, ZHONG Zhendong. Mechanism of Protective Effect of Raddeanin A on Hepatic Ischemia-reperfusion in Rats [J]. Laboratory Animal and Comparative Medicine, 2021, 41(1): 55-60.
[2]	ZHANG Xiaojie, JIANG Lei. Molecular Mechanism of Resveratrol Against Myocardial Ischemia-Reperfusion Injury in Rats Based on Network Pharmacology [J]. Laboratory Animal and Comparative Medicine, 2020, 40(6): 496-505.
[3]	HE Dawei, HE Aolin, ZHOU Minghui, YU Yaping, ZHANG Minghua. Effects of Sodium Oxalate on Autophagy and Apoptosis of Cholangiocarcinoma Cells#br# [J]. Laboratory Animal and Comparative Medicine, 2020, 40(5): 403-.
[4]	KANG Yu, YANG Xiaofang. Protective Effect and Mechanism of Nanoliposomal Quercetin on Focal Cerebral Ischemia-reperfusion Injury in Rats [J]. Laboratory Animal and Comparative Medicine, 2020, 40(2): 116-122.
[5]	LI Yan, KONG Jian-jun, CHEN Zi-qi, ZHU Cong-cong. Inhibitory Effect of shRNA TRPV4 Gene on Intervertebral Disc Degeneration in Scoliosis Rat Model [J]. Laboratory Animal and Comparative Medicine, 2019, 39(5): 356-363.
[6]	JING Jin, ZHANG Hai-jun, DU Li-li, JI Gui-qing, SHAO Yi-xiang. Experimental Study on Proliferation, Apoptosis and Migration of Eyelid Fibroblasts in B6-Co Mice [J]. Laboratory Animal and Comparative Medicine, 2019, 39(3): 213-219.
[7]	XIAO Bang, LI Li, YU Chen-lin, ZHAO Shan-min, LIN Li-fang, YANG Wen-jing, CONG Wei, CUI Shu-fang. Influence of Cobalt Chloride Induced Hypoxia on Proliferation and Apoptosis of Hepatic Stellate Cells in Naked Mole Rat [J]. Laboratory Animal and Comparative Medicine, 2016, 36(1): 66-71.
[8]	ZHANG Quan, ZHU Hui-xia, LI Ling-yu, TAN Hai-ming, XUE Zheng-feng. Research Progress on Sendai Virus against Tumors [J]. Laboratory Animal and Comparative Medicine, 2014, 34(6): 515-518.
[9]	ZHAO Shan-min, LIN Li-fang, XIAO Bang, WANG Yun-hui, GONG Chen, ZHANG Lu, YU Chen-lin, TANG Qiu, SUN Wei, CUI Shu-fang. Comparative Effects of Hypoxia on Autophagy and Apoptosis of Naked Mole Rat Fibroblasts [J]. Laboratory Animal and Comparative Medicine, 2014, 34(5): 405-410.
[10]	JIANG Yan, WANG Wei, LI Ze-zheng, CHENG Jin, WANG Wei-wei, ZHANG Jin-yuan. Establishment and Evaluation of Acute Kidney Injury Mice Model by Ischemia Reperfusion and Cisplatin Induction [J]. Laboratory Animal and Comparative Medicine, 2014, 34(3): 187-192.
[11]	YE Hong-mei, ZHONG Chun-yan, Huang min-xian, Lu Jun-hua. The Protecting Machanism of Litchi Seed Aqueous Extracts on Learning and Memory Damage Induced by D-galactose in Mice [J]. Laboratory Animal and Comparative Medicine, 2013, 33(4): 285-289.
[12]	QU Jing -kai, WANG Hong-yan, QI Ya-li, CHEN Yu-bing, SONG Xiang-fu, GONG Shou-liang. The Expression of Survivin mRNA on Thymus Tissue Apoptosis Induced Radiation [J]. Laboratory Animal and Comparative Medicine, 2013, 33(1): 60-63.
[13]	WANG Cui-ling, WANG Zeng-song, XIA Shu-qi, GUO Gui-ling, XIE Fei-qun, LI Wen-tang, NIU Li-hong, LUO Qun-huang, ZHANG Yi-jun. IL-12 Facilitate the Recovery of Hematopoietic Stem Cells after Ionizing Radiation in Rat [J]. Laboratory Animal and Comparative Medicine, 2012, 32(3): 218-221.
[14]	WANG Xiao1，WANG Ning1，LIN Chuan-quan1，XU Qing-wen2，FU Yun1，LIU Jin-yuan3. Myocardial Injury in Rabbit Congestive Heart Failure Models and the Relationship Thereof to Nitric Oxide [J]. , 2010, 30(5): 329-324.
[15]	YIN Guang-mei1,YU Lin-sheng2,ZHENG Yuan-yuan2,YI Ji-pu2,YE Guang-hua2,WU Shu-zhen2,ZHAO Kang2. Effects of Curcumin on Brain Damage Repair in Cerebral Cortex and Hippocampus Tissue of Rats with Hypoxic Ischemic [J]. , 2010, 30(3): 158-162.