水迷宫水域调节方法的改良

›› 2008, Vol. 28 ›› Issue (4): 243-245.

水迷宫水域调节方法的改良

第二军医大学 1.第一附属医院药学部，上海 200433;2.新药评价中心，上海 200433

收稿日期:2008-03-22 出版日期:2008-04-30 发布日期:2008-04-30

A new method to make water for the Morris water maze

1. Department of Pharmacy, Changhai Hospital, Secondary Mi litary Medical University, Shanghai 200433, China. 2. New drug Evaluation Center, Secondary Mi litary Medical University, Shanghai 200433, China

Received:2008-03-22 Online:2008-04-30 Published:2008-04-30

摘要/Abstract

摘要： 目的开发经济实用的水迷宫实验水域调节方法，降低实验成本，为水迷宫实验提供便利条件。方法利用食用色素调节水域浊度与颜色，筛选合适的浓度与混合比例。结果 10 mg/L白色素溶液足以满足浊度要求；5 mg/L黑色素溶液足以满足颜色要求；含有10 mg/L白色素和5 mg/L黑色素的溶液同时满足浊度和颜色的要求。结论 10 mg/L白色素溶液可直接用作深色动物水迷宫实验的水域；含有10 mg/L白色素和5 mg/L黑色素的溶液满足白色动物水迷宫实验的水域要求。

关键词: 实验经济学, Morris水迷宫, 水域, 食用色素

Abstract: Objective To develop an economical and practical method by adjusting water color and turbidity for Morris water maze Methods Pigment was used to adjust the color and turbidity of the water by screening the suitable concentration and proportion. Results 10 mg/L white pigment was suitable for the requirenent of turbidity, 5 mg/L melanin for color, and the mixture of 10 mg/L white pigment and 5 mg/L melanin for the turbidity and color perfectly. Conclusion 10 mg/L white pigment could be used for Morris water maze tests in small pigmented rodents and the mixture of 10 mg/L white pigment and 5 mg/L melanin solution was suitable in the small albino rodents.

Key words: Experiment economics, Morris water maze, Colorant

刘艳霞1，胡晋红1，郑杰民2，朱全刚1，孙创斌1. 水迷宫水域调节方法的改良[J]. , 2008, 28(4): 243-245.

LIU Yan-xia1，HU Jm-hong1，ZHU Quan-gang1，LIU Ji-yong, ZHENG Jie-min2 . A new method to make water for the Morris water maze[J]. , 2008, 28(4): 243-245.

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