实验动物与比较医学 ›› 2006, Vol. 26 ›› Issue (1): 54-58.

• 论文 •    

肥厚性心肌病模型及版纳微型猪近交系的应用

  

  1. 1.广东药学院广东省药物控释制剂重点实验室,广州 510240;2.云南农业大学云南省版纳微型猪近交系重点实验室,昆明 650201

Hypertrophic Cardiomyopathy Animal Model and Application of Banna Minipig Inbred Line

  1. 1.Key Laboratory of Controlled Release Drug Preparations of Guangdong Province, Guangdong College of Pharmacy, Guangzhou 510240,China;2.Key Laboratory of Banna Minipig Inbred Line of Yunnan Province, Yunnan Agricultural University, Kunming 650201,China

摘要: 本文综述了肥厚性心肌病发病机制和肥厚性心肌病动物模型的应用情况。介绍了版纳微型猪近交系独特的近交背景和在解剖学上与人类接近的特点,并探讨了将版纳微型猪近交系应用于人类肥厚性心肌病动物模型研究的前景。

Abstract: The pathogeneses and current situation of animal models of hypertrophic cardiomyopathy was reviewed. With the unique inbred genetic backgrounds and resemblance with what of human beings in anatomy and physiology, the prospective of the application of Banna Minipig Inbred Line as the model of hypertrophic cardiomyopathy was explored.