›› 2002, Vol. 22 ›› Issue (3): 141-144.

• 论文 • 上一篇    下一篇

大鼠创伤性肠粘连模型的制备及黄厚排气颗粒对其粘连程度的影响

  

  1. 安徽省药物研究所研究四室,合肥 230022
  • 收稿日期:2002-05-01 出版日期:2002-01-25 发布日期:2013-03-19
  • 基金资助:

    安徽省优秀青年基金资助

Preparation of Traumatic Intestinal Adhesion Model of Rats and the Effect of Huanghou Paiqi Granule on the Degree of Intestinal Adhesion

  1. Department of Laboratory IV,Anhui Institute of Pharmacy, Hefei 230022, China
  • Received:2002-05-01 Online:2002-01-25 Published:2013-03-19

摘要: 为筛选出操作方法简便,结果稳定可控的大鼠创伤性肠粘连模型,观察中药复方黄厚排气颗粒对其粘连程度的影响,选用SD大鼠,手术造成肠粘连模型,用中药复方2.5、5.0、10.0g/kg连续治疗7d后观察肠粘连程度。结果表明,以盲肠型动物模型的制备较为理想,手术易于操作,结果稳定可控。用中药复方治疗后模型动物的肠粘连程度得到明显改善。提示黄厚排气颗粒对术后肠粘连有一定的预防作用。

关键词: 肠粘连, 动物模型, 中医药治疗

Abstract: To screen out the steady and controllable animal model and study the effect of the compound TCM on the degree of intestinal adhesion in rats after surgery,the SD rats of intestinal adhesion model alter surgery fed with the compound TCM Huanghou Paiqi Granule at the dosage of 2.5、5.0、10.0g·kg-1·d-1 continuously for 7 days for studying its effect on the degree of intestinal adhesion. The Results showed that the caecum model was easy to establish,steady and controllable, the Compound TCM could obviously improve the degree of intestinal adhesion in rats after surgery.

Key words: Huanghou Paiqi Granule, Intestinal adhesion, Animal model, TCM therapy