›› 2001, Vol. 21 ›› Issue (2): 98-99.

• 论文 • 上一篇    下一篇

小鼠子宫自发性神经纤维样平滑肌肉瘤的病理学观察

  

  1. 上海医药工业研究院毒理室,上海 200437
  • 收稿日期:2001-03-15 出版日期:2001-01-25 发布日期:2013-03-19

Pathological Observation of a Spontaneous Neoplastic Lesion in Mouse

  1. Department of Toxicology ,Shanghai Institute of Pharmaceutical Industry,Shanghai 200437 ,China
  • Received:2001-03-15 Online:2001-01-25 Published:2013-03-19

摘要: 报告了一例发生在实验小鼠子宫的自发性肿瘤,病理组织学检查表明,肿瘤组织的主要部分由密集而交错成束的梭形细胞组成,排列呈栅栏状或旋涡状,部分区域结构较疏松并有变性坏死,还有淋巴结转移。病理诊断为一种较为特殊的神经纤维样平滑肌肉瘤。

关键词: 小鼠, 自发性肿瘤, 平滑肌肉瘤

Abstract: Spontaneous neoplastic lesions are often observed in aged experimental ani-mals. The case reported here was a spindle cell sarcoma in mouse. The original site was uterus with distant lymph nodes metaslases. The neoplasma was composed of interlac-ing bundles of elongated spindle cells with palisading of nuclei. Some areas show degen-eration and necrosis. It was not very typical in ordinary appearance of leiomyosarcoma, but a special type of smooth muscle tumours.

Key words: Mouse , Spontaneous neoplast ic lesion