›› 2001, Vol. 21 ›› Issue (2): 118-121.

• 论文 • 上一篇    下一篇

水痘-带状疱疹病毒感染的动物模型

  

  1. 1.成都中医药大学99级硕士研究生,成都 610075;2.广州中医药大学热带医学研究所;3.四川省中医药研究院
  • 收稿日期:2000-12-11 出版日期:2001-01-25 发布日期:2013-03-19

Animal Models of Varicella-Zoster Virus Infections

  1. 1.Chengdu University of TCM, Chengdu 610075,China;2.Tropical Medicine Institute,Guangzhou University of TCM,Guangzhou 510407,China ;3.Sichuan Institute of TCM 610041,China
  • Received:2000-12-11 Online:2001-01-25 Published:2013-03-19

摘要: 对近20年来水痘-带状疱疹病毒(VZV)感染的动物模型进行了简单的回顾,并逐一对非人类灵长目动物、豚鼠、大鼠、小鼠模型的建立方法、病毒检测及其应用进行了论述。VZV感染的动物模型的不断完善及其系统、深入的研究,对于探索VZV感染的机理及研制疫苗与抗病毒药物具有重要的意义。

关键词: 水痘-带状疱疹, 动物模型

Abstract: The researches on animal models infected by varicella-zoster virus (VZV) in the latest twenty years were retrospected. The authors summarized the methods used both in the establishment of the models on non-human primates,guinea pig, rat and mouse and the methods for the detection of the virus,and outlined the applications of the models. To compare, summarize and analyze these documents is very beneficial to studying the mechanism of VZV infection and developing vaccine and anti-virus medicines.

Key words: Varicella-zoster virus , Animal model