关键词: Lewis肺癌, 放射免疫测定, EGF, 人参, 人参皂甙, 小鼠

Abstract: C57BL/6 mice were implanted with Lewis lung cancer cell(2×10⁷) and treated every day with Ginseng decoction and Panaxosides 3 days later. Serum EGF content were detected by radioimmunoassay 2 weeks after the implantion. The EGF content were 0.18±0.11,0.28±0.09,0.16±0.10 and 0.29±0.11μg/L respectively in normal,non-treated tumor bearing,Ginseng decoction and panaxosides treated tumor bearing mice. The tumor weight of the Ginseng decoction treated mice was 3.6±0.8g,higher than that of non -treated mice(2.8±0.53g),and more higher than that of panaxosides treated mice(1.1±0.59g). The results suggested that the growth of tumor may be closely related to EGF,and Ginseng could accelerate the utilization of EGF and promote the growth of tumor. Panaxosides is not the effective component in Ginseng for accelerating the growth of tumor and utilization of EGF.

Key words: Lewis lung cancer, Radioimmunoassay EGF Ginseng, Decoction, Panaxosides, Mice