腔内超声显象法对家兔动脉脂质斑块的在体量化

›› 1997, Vol. 17 ›› Issue (2): 74-76.

腔内超声显象法对家兔动脉脂质斑块的在体量化

苏州医学院附属第一医院心血管病研究室，苏州 215006

收稿日期:1997-01-27 出版日期:1997-01-25 发布日期:2013-03-19

Quantitative Assessment of Lipid Deposits in Arterial Walls by Intravascular Ultrasound Imaging in Rabbits

Research Laboratory of Cardiology, The First Affiliated Hospital of Suzhou Medical College, Suzhou 215006

Received:1997-01-27 Online:1997-01-25 Published:2013-03-19

摘要/Abstract

摘要： 对20只动脉硬化的雄性新西兰兔作了血管腔内超声（IVUS）显象和病理学检查，测定脂质斑块的截面积、厚度以及病变血管管腔的截面积和直径。结果：实验家兔均有动脉脂质沉积的病理改变；超声显象示血管壁内面有突向腔内的低回声区，其面积为0.71±0.26mm²，厚度达0.27±0.09mm，与病理学检查所见斑块相符，提示用IVUS对脂质斑块作在体量化是切实可行的，可为在体测量脂质斑块提供新的手段。

关键词: 血管腔内超声显象, 脂质斑块, 在体量化, 家兔

Abstract: To develop a new means of quantitating iipid deposits in vivo the authors performed intravascular ultrasound (IVUS) imaging on twenty atherosclerotic male New Zealand White rabbits, measured the sectional area and thickness of the plaques, the lumen area and diameter in lesion arteries. The results revealed that all of the rabbits were found with lipid deposits with the features of hypoechosic areas in IVUS image that adhered to the inner of the arterial walls and were coincided with the histopathologic observations. The sec tional area of the plaques was 0.71±0.26mm², and the thickness was 0.27±0.09mm. The authors consider that IVUS imaging would be a new means of quantitative assessment for the lipid deposits in vivo.

Key words: Intravascular ultrasound imaging, Quantitative assessment, Lipid deposit Rabbit

顾振良, 方秀英, 蒋文平. 腔内超声显象法对家兔动脉脂质斑块的在体量化[J]. , 1997, 17(2): 74-76.

GU Zhen-Liang, FANG Xiu-Ying, JIANG Wen-Ping. Quantitative Assessment of Lipid Deposits in Arterial Walls by Intravascular Ultrasound Imaging in Rabbits[J]. , 1997, 17(2): 74-76.

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