›› 1995, Vol. 15 ›› Issue (4): 201-205.

• 论文 • 上一篇    下一篇

60CO-γ射线辐照消毒大鼠与小鼠饲料的效果

  

  1. 1.中国科学院上海药物研究所;2.中国科学院上海实验动物中心
  • 收稿日期:1995-01-18 出版日期:1995-01-25 发布日期:2013-03-19

Effects of 60Co-γ Radiation on Feed for Rats and Mice

  1. 1.Shanghai Institute of Materia Medica, Chinese Academia of Sciences, Shanghai 200031;2.Shanghai Laboratory Animal Center,Chinese Academia of Sciences
  • Received:1995-01-18 Online:1995-01-25 Published:2013-03-19

摘要: 60CO-γ射线辐照大鼠与小鼠颗粒饲料的有效灭菌剂量和辐照后饲料的营养成分。有效保存期及饲喂效果进行了研究。结果表明,SPF级动物饲料的有效灭菌剂量为25kGy,辐照灭菌后的有效保存期至少为90d,而以30kGy辐照剂量灭菌的饲料可以保存180d.饲料经辐照灭菌后,仅维生素B1减少20%左右,其余营养成分无明显损失。而以高压蒸汽法(121℃,30min)灭菌的饲料其粗蛋白和维生素等均有不同程度的损失,尤其是维生素B1损失约50%。以两种不同方法灭菌的饲料分别饲喂裸小鼠,结果:辐照饲料组裸鼠的体重显著高于高压灭菌组(P<0.05)。

关键词: 饲料, 60Co-&gamma, 射线, 灭菌剂量, 营养成分, 保存期, 饲喂效果

Abstract: To determine the effective sterilizing dose of 60Co-γ ray for rat and mouse feed, the granulated feed was radiated with 60Co-γ ray in different doses. The result showed that the effective dose was 25 kGy. The storage term of the radiated feed was at least 90 d. When the feed was radiated with a dose of 30 kGy, its storage term exceeded 180 d. No marked distruction of the nutrients of the radiated feed was found except vitman B1 which decreased about 20% , while in the autoclaved (121℃, 30 min) feed the crude protein, amino acids and vitmans decreased, especially the vitman B1 decreased about 50%. The weanling nude mice fed with the radiated feed (25 kGy) for one month grew faster than those fed with the autoclaved feed (P<0.05).

Key words: "Feed, 60Co-&gamma, radiation, Sterilized dose, Nutrient, Storage term, Feeding effect "