›› 1994, Vol. 14 ›› Issue (2): 63-66.

• 论文 •    下一篇

犬肠缺血——再灌流后血液及组织内超氧化物歧化酶的改变

  

  1. 中国人民解放军304医院
  • 收稿日期:1994-01-10 出版日期:1994-04-25 发布日期:1994-04-25

The Changes of Superoxide Dismutase Contents in Blood and Tissues after the Injury of Bowel Ischemia and Reperfusion in Dogs

  1. 304th Hospital of PL A, Beijing 100037
  • Received:1994-01-10 Online:1994-04-25 Published:1994-04-25

摘要: 用饲菌加肠系膜上动脉不全阻断的方法,观察实验大肠缺血—再灌流所导致的肝、肺功能改变与全血及组织内超氧化物歧化酶(SOD)含量的关系。结果发现,犬肠缺血——再灌流后血液及肺、肝组织内SOD含量明显下降并伴有肺、肝功能的明显损害。这提示,肠缺血——再灌流导致了机体氧化能力的明显下降,其肝、肺功能的损伤程度与其组织内SOD的下降水平有关。

关键词: 超氧化物歧化酶, 缺血&mdash, 再灌流

Abstract: The portal circulation was reduced by partial occlusion of the superior mesen-tcric artery, and the consequent influences on superoxide dismutase (SOD) and or-gans functions were studied.The results showed that there was a marked reduction in SOD contents in the liver, lung and blood accompanics by the functional impai-rment of the organs damage after ischemia and reperfusion.

Key words: Superoxide dismutase, Ischemia and reperfusion