实验动物与比较医学 ›› 1993, Vol. 13 ›› Issue (4): 208-210.
• 论文 •
摘要： 应用SD大鼠，观察了连续3个月饲喂小剂量乙醇对肝脏γ谷氨酰转肽酶（γ-GT）活性的影响，及试管内乙醇（最终浓度从34mmol/L到170mmol/L）对γ-GT纯酶活性的抑制作用。结果表明：整体实验中乙醇对肝脏γ-GT活性无明显影响，离体实验中乙醇对γ-GT活性有轻度的抑制作用，且随乙醇浓度的增加呈渐增趋势。
Abstract: To study the effects of chronic alcohol intake on γ-glutamyl transpeptidase （γ-GT）activity in rat liver. Male and female Sprague Dawley rats were fed with 20% ethanol at the dose of 790 mg/kg body weight per day for 3 months. The γ-GT activity was measured at 1，2，and 3 month of experiment. No significant differences were found in γ-GT activity between experimental and control rats, however γ-GT activity was inhibited by ethanol in vitro.
. Effects of Chronic Alcohol Intake on Y-Glutamyl Transpeptidase Activity of Rat Liver[J]. Laboratory Animal and Comparative Medicine, 1993, 13(4): 208-210.
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