Metabolic Disease Animal Models induced by High-fat Diets

doi:10.12300/j.issn.1674-5817.2021.050

Abstract

Abstract: High-fat diets are often used to induce models with nutritional abnormalities and stimulate human diseases, which are used to explore the mechanism of disease development and widely used in clinical hypothesis study. In order to provide theoretical and practical basis for researchers in this field, recent advances on animal models of metabolic diseases induced by high-fat diets were reviewed, and the mechanisms underlying disease development and the respective roles of nutrient components of the diets were also discussed.

Key words: High-fat diet, Metabolic diseases, Animal model, Mechanisms

CLC Number:

Q95-33
R-332

LUO Jianbo, LI Junhui, WANG Haijiang, ZHOU Xiaoyu, ZENG Tao, ZHOU Jia, ZHU Xianjun. Metabolic Disease Animal Models induced by High-fat Diets[J]. Laboratory Animal and Comparative Medicine, 2021, 41(1): 70-78.

Figures/Tables 6

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