›› 1999, Vol. 19 ›› Issue (2): 96-96.

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A Focal Cerebral Ischemia Model by Occluding Middle Cerebral Artery in Rat

  

  • Received:1998-08-11 Online:1999-01-25 Published:2013-03-19

Abstract: The single lateral middle cerebral arteries (MCA) of SD rats were occluded with electric heating coagulation following the ligation of ipsilaternl common carotid artery (CCA). After 7 clays,the focal cerebral ischemia in the animals were evaluated with a neurologic examination grading system,histochemistry staining techniques and a computer image analytic system. The results showed that focal cerebral ischemia model was duplicated . ancl was reliable and practical for the studies on brain infarction and its therapy.

Key words: "Brain infarction, Middle cerebral artery, Animal model, Neurologic deficiency, Rat "