Abstract: 《Public Health Service Policy on Humane Care and Use of Laboratory Animals》is an important part of the legal system of laboratory animal welfare in the United States. It is the main policy for U.S. government to implement the management of laboratory animal industry, and also the foundation for caring and using laboratory animals in scientific research. The PHS Policy covers all the research activities conducted or supported by the Public Health Service (PHS). The Office of Laboratory Animal Welfare, National Institute of Health (NIH), which has responsibility for the general administration and coordination of the Policy, revised the PHS Policy in June 2015. The authors translated the full-text PHS Policy into Chinese and provided reference to understand and study the laws and regulations on laboratory animal welfare of U.S. The essay may be used for reference to learn the methods and experience on humane care and use of laboratory animals.

Key words: Public Health Service, Humane Care and Use, Laboratory Animals, Policy