Observation on Mitomycin's Effect for Reducing Fibrous Tissue Hyperplasia after KTP Nd:YAG laser in Rabbit

doi:10.3969/j.issn.1674-5817.2012.05.013

Abstract

Abstract: Objective To observe the effect of Mitomycin(MMC) for reducing fibrous tissue hyperplasia after KTP Nd:YAG laser recanalisation in rabbit. Method The rabbit model of lacrimal duct obstruction was established, and the model rabbit was divided into two groups injecting with saline solution and MMC respectively. Result The appearance of lacrimal duct part obstruction and fibrous tissue hyperplasia was later in the MMC group, and the fibrous tissue hyperplasia is lighter. Conclusion MMC can reduce fibrous tissue hyperplasia after KTP Nd:YAG, and improve the success rate of KTP Nd:YAG laser recanalization.

Key words: Mitomycin(MMC), Lacrimal duct stenosis, Fibrous tissue hyperplasia, Rabbit

CLC Number:

Q95-33

LI Jin, YANG Wen-lei, DU Xiao-yan, ZHANG Lin. Observation on Mitomycin's Effect for Reducing Fibrous Tissue Hyperplasia after KTP Nd:YAG laser in Rabbit[J]. Laboratory Animal and Comparative Medicine, 2012, 32(5): 431-435.

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