Abstract: Objective To study the genetic variation and inbreeding of inbred Wuzhishan Minipig(WZSP) breeds. Methods Twenty-six microsatellite loci were utilized to analyze the genetic diversity of the inbred WZSP breeds. Number of alleles (N) of each locus in the breeds was counted, the rate of homozygote, polymorphism information content (PIC) and heterozygosity (H) were calculated. Results The 180 alleles in WZSP breeds were detected, the average allelic number per locus was 6.92, the mean homozygosity was 56.57%. The average value of PIC and H was 0.6042 and 0.4478 respectively. Conclusion The inbred WZSP breeds is a genetically stabilized breed with high homozygosity.

Key words: Wuzhishan Minipig (WZSP), Microsatellite, Genetic variation