Abstract: Objective To establish genetic quality standard of inbred Chinese hamster (Cricetulus griseus). Methods Based on investigating a large number of related literatures, according to Laboratory animal-Genetic quality control of mammalian laboratory animals (GB14923-2010) and the theory of population genetics, the genetic quality standard of inbred Chinese hamster was established. The genetic quality of Chinese hamster was detected by microsatellite markers which were obtained from a Chinese hamster genomic enrichment library and the PCR primers of them were designed. Results The genetic quality standard and the detection method of inbred Chinese hamster were preliminarily established. Conclusion The establishment of genetic quality standard of inbred Chinese hamster will standardize the breeding and reproduction of inbred Chinese hamster and promote the further improvement of genetic quality standard system of laboratory animals in China.

Key words: Chinese hamster, Genetic quality standard, Microsatellite locus