Abstract: The body and organs weight of KM mice from 6 colonies in China were mea-sured and the coefficicent of the organ weight were calculated. The results showed that the difference among 6 colonies of KM mice was found through ANOVA analysis 0.05），and the growth of body and the development of most organs of the mice bred in barrier system increased relatively fast, but the development of spleen and adrenal was relatively slow. The authors suggested that an accelerated research on the standardiza-tion of Chinese KM mice would be critically faced.

Key words: KM mice , Organ weight , Coefficicent of organ weight , Comparative analysis