The Current Status of Laboratory Animal License Administration in Guangdong Province

doi:10.12300/j.issn.1674-5817.2022.107

Abstract

Abstract:

This study examined and summarized the operations and achievements of laboratory animal license administration in Guangdong Province and presents preliminary suggestions based on the deficiencies in the current administration. The study utilized laboratory animal licensing data of Guangdong Province obtained from the National Laboratory Animal License Inquiry and Administration System, and uses a combination of statistical analysis, literature review, and comparative research. Various aspects of the workings of the laboratory animal license administration in Guangdong Province were analyzed, including license issuance, regional distribution, animal species, organization types, facility scale, and development trend of laboratory animal license administration in Guangdong Province to identify areas of improvements. The following measures were recommended to the Guangdong Province: increasing social awareness about the importance of using laboratory animals, promoting the publicity and implementation of laws and regulations on laboratory animals, strengthening the strategic resource reserve of experimental animals, improving the management system of aquatic laboratory animals, and optimizing information management. Through such measures, we aimed to provide reference for the administration of laboratory animals in other regions.

Key words: Laboratory animals, Administrative management, License, Guangdong Province

CLC Number:

Q95-33

Huiping LI,Chujun LIANG,Weibo ZHAO. The Current Status of Laboratory Animal License Administration in Guangdong Province[J]. Laboratory Animal and Comparative Medicine, 2022, 42(6): 577-582. DOI: 10.12300/j.issn.1674-5817.2022.107.

Figures/Tables 4

References 13

1	黄韧, 陈乾生, 张镇威, 等. 广东省实验动物工作的现状和发展对策[J]. 科技管理研究, 1990, 10(1):38-40.
	HUANG R, CHEN Q S, ZHANG Z W, et al. Present situation and development countermeasures of laboratory animal work in Guangdong Province[J]. Sci Technol Manag Res, 1990, 10(1):38-40.
2	广东省科学技术委员会. 广东省实验动物管理办法: 粤府函〔1988〕136号[A]. 1988.
	Guangdong Provincial Science and Technology Commission.Administrative measures of Guangdong Province on laboratory animals: YFH-1988-136[A]. 1988.
3	广东省科委. 关于在科研计划和科研成果管理中执行实验动物合格证制度的通知[A]. 1995.
	Guangdong Provincial Science and Technology Commission. Notice on implementing the certificate system for laboratory animals in the scientific research plans and the management of scientific research achievements[A]. 1995.
4	胡娟峰, 曾林, 战大伟, 等. 实验动物许可证管理现状分析[J]. 中国比较医学杂志, 2008, 18(10):56-59.
	HU J F, ZENG L, ZHAN D W, et al. Analysis of the current situation of laboratory animal license[J]. Chin J Comp Med, 2008, 18(10):56-59.
5	广东省科技厅. 广东省实验动物许可证管理细则(试行)[A]. 2002.
	Department of Science and Technology of Guangdong Province. Detailed rules for the administration of laboratory animal licenses in Guangdong Province (for trial implemen-tation)[A]. 2002.
6	广东省人民政府. 广东省实验动物管理条例: 2019年修正版[A/OL]. 2022-02-07. .
	People's Government of Guangdong Province. Regulations of Guangdong Province on the administration of laboratory animals: Revised in 2019[A/OL]. 2022-02-07. .
7	广东省科技厅关于印发«广东省科技厅关于实验动物行政处罚自由裁量权的规定»和«广东省科学技术厅实验动物行政处罚自由裁量权执行标准»的通知[A/OL]. 2016.
	Notice on printing and distributing the Provisions of the Department of Science and Technology of Guangdong Province on the Discretion of Administrative Punishment of Laboratory Animals and the Executive Standard of the Department of Science and Technology of Guangdong Province on the Discretion of Administrative Punishment of Laboratory Animals[A/OL]. 2016. .
8	广东省科学技术厅关于实验动物行政处罚自由裁量权的规定[A/OL]. 2022. .
	The provisions of the Department of Science and Technology of Guangdong Province on the discretion of administrative punishment of laboratory animals[A/OL]. 2022. .
9	全国实验动物许可证查询管理系统[DB/OL]. 2018. .
	National laboratory animal license inquiry management system [DB/OL]. 2018. .
10	李彪, 余亮, 陈梅丽, 等. 广东省实验动物许可证管理工作的现状及对策[J]. 中国比较医学杂志, 2014, 24(6):73-77. DOI:10.3969/j.issn.1671.7856.2014.006.016 .
	LI B, YU L, CHEN M L, et al. Present situation and strategy of laboratory animal license management in Guangdong Province[J]. Chin J Comp Med, 2014, 24(6):73-77. DOI:10.3969/j.issn.1671.7856.2014.006.016 .
11	广东省实验动物科技发展 30周年工作会议在广州隆重召开[EB/OL]. 2018 [2022-06-30]. .
	The working conference for the 30th anniversary of the development of laboratory animal science and technology in Guangdong Province is held in Guangzhou[EB/OL]. 2018 [2022-06-30]. .
12	李会萍, 王晓明, 杨锦淳, 等. 2018年我国实验动物许可证管理的现状及分析[J]. 中国比较医学杂志, 2019, 29(7):131-136. DOI: 10.3969/j.issn.1671-7856.2019.07.022 .
	LI H P, WANG X M, YANG J C, et al. Current status and analysis of the Chinese laboratory animal license administration in 2018[J]. Chin J Comp Med, 2019, 29(7):131-136. DOI: 10.3969/j.issn.1671-7856.2019.07.022 .
13	严强. 创新实验动物科技助力创新强省建设[N]. 南方日报, 2018-10-29(A05).
	YAN Q. Innovating experimental animal science and technology to help building a strong province through innovation[N]. Nanfang Daily, 2018-10-29(A05).

区域 Region	生产许可/个 Production license/piece	使用许可/个 Use license/piece	合计/个 Total/piece	比例/% Proportion/%
广州Guangzhou	22	108	130	57.018
深圳Shenzhen	0	27	27	11.842
佛山Foshan	5	9	14	6.140
中山Zhongshan	1	11	12	5.263
东莞Dongguan	0	10	10	4.386
珠海Zhuhai	1	6	7	3.070
湛江Zhanjiang	3	3	6	2.632
汕头Shantou	0	5	5	2.193
肇庆Zhaoqing	2	2	4	1.754
云浮Yunfu	1	3	4	1.754
清远Qingyuan	0	3	3	1.316
韶关Shaoguan	0	2	2	0.877
江门Jiangmen	2	0	2	0.877
惠州Huizhou	0	1	1	0.439
揭阳Jieyang	0	1	1	0.439
合计Total	37	191	228	100.000

区域 Region	生产许可/个 Production license/piece	使用许可/个 Use license/piece	合计/个 Total/piece	比例/% Proportion/%
广州Guangzhou	22	108	130	57.018
深圳Shenzhen	0	27	27	11.842
佛山Foshan	5	9	14	6.140
中山Zhongshan	1	11	12	5.263
东莞Dongguan	0	10	10	4.386
珠海Zhuhai	1	6	7	3.070
湛江Zhanjiang	3	3	6	2.632
汕头Shantou	0	5	5	2.193
肇庆Zhaoqing	2	2	4	1.754
云浮Yunfu	1	3	4	1.754
清远Qingyuan	0	3	3	1.316
韶关Shaoguan	0	2	2	0.877
江门Jiangmen	2	0	2	0.877
惠州Huizhou	0	1	1	0.439
揭阳Jieyang	0	1	1	0.439
合计Total	37	191	228	100.000

单位性质 Unit attribute	生产许可/个 Production license/piece	使用许可/个 Use license/piece	合计 Total/piece	比例/% Proportion/%
生物医药Biomedicine	19	95	114	50.0
高校College	6	34	40	17.5
科研院所Research institutes	3	23	26	11.4
医疗卫生Medical hygiene	2	22	24	10.5
检测机构Testing facility	0	12	12	5.3
其他企业Other companies	7	5	12	5.3
合计Total	37	191	228	100.0

单位性质 Unit attribute	生产许可/个 Production license/piece	使用许可/个 Use license/piece	合计 Total/piece	比例/% Proportion/%
生物医药Biomedicine	19	95	114	50.0
高校College	6	34	40	17.5
科研院所Research institutes	3	23	26	11.4
医疗卫生Medical hygiene	2	22	24	10.5
检测机构Testing facility	0	12	12	5.3
其他企业Other companies	7	5	12	5.3
合计Total	37	191	228	100.0

[1]	LIU Wentao, LUO Yanhong, LONG Yongxia, LUO Qihui, CHEN Zhengli, LIU Lida. Common Environmental Problems and Testing Experiences in Laboratory Animal Facilities in Sichuan Province [J]. Laboratory Animal and Comparative Medicine, 2025, 45(4): 483-489.
[2]	TAN Dengxu, MA Yifan, LIU Ke, ZHANG Yanying, SHI Changhong. Reshaping Intercellular Interactions: Empowering the Exploration of Disease Mechanisms and Therapies Using Organoid Co-Culture Models [J]. Laboratory Animal and Comparative Medicine, 2025, 45(3): 309-317.
[3]	SHEN Huangyi, HUANG Yufei, YANG Yunpeng. Research Progress on Characteristics Analysis of Gut Microbiota and Its Sex Differences in Laboratory Animals [J]. Laboratory Animal and Comparative Medicine, 2025, 45(3): 349-359.
[4]	LIU Lida, CHEN Bing, XIE Na, LIU Li, ZHUANG Siqi, ZOU Yixing. Survey Report Analysis on Parasitic and Microbial Quality of Laboratory Animals in Sichuan Province, 2017-2023 [J]. Laboratory Animal and Comparative Medicine, 2024, 44(6): 654-660.
[5]	LIU Yishu, CAI Liping. Advances and Challenges of Using Experimental Pigs in Da Vinci Surgical Robot Training [J]. Laboratory Animal and Comparative Medicine, 2024, 44(6): 667-674.
[6]	CHEN Bing, ZOU Yixing, WANG Jingdong. Analysis on Current Status and Countermeasures for Laboratory Animal Management in Sichuan Province Based on Administrative Licensing [J]. Laboratory Animal and Comparative Medicine, 2024, 44(5): 560-566.
[7]	ZHAO Yong. Three Dimensions of Animal Experiment Ethics: Analysis Based on Value of Life, Animal Welfare, and Risk Prevention [J]. Laboratory Animal and Comparative Medicine, 2024, 44(4): 445-454.
[8]	DENG Shaochang, LIN Danrong, LIANG Chujun, LEI Weiqiao, YANG Jinchun, ZHAO Weibo. Analysis of Institutional Characteristics and Implementation of Guangdong Province Laboratory Animals Ordinance in the Past Decade [J]. Laboratory Animal and Comparative Medicine, 2024, 44(4): 455-462.
[9]	SUN Qiang. History, Current Status, Challenges and Opportunities of Laboratory Monkey Industry in China [J]. Laboratory Animal and Comparative Medicine, 2024, 44(4): 343-356.
[10]	Lingzhi YU, Xiaofeng WEI, Ming LI, Zhihao KONG. Comparison of Methods between Soiled Bedding Sentinels and Exhaust Air Dust PCR for Health Monitoring of Rodent Laboratory Animals [J]. Laboratory Animal and Comparative Medicine, 2024, 44(3): 321-327.
[11]	Meitong LIU, Zhang CHEN, Zhaoqiang ZHANG, Di FAN, Zhan HU, Hailing MA. Formulation of Emergency Response Plan for Laboratory Animal Biosafety Emergencies in Hunan Province [J]. Laboratory Animal and Comparative Medicine, 2024, 44(3): 328-334.
[12]	Meitong LIU, Zhang CHEN, Zhaoqiang ZHANG, Di FAN, Zhan HU, Hailing MA. Investigation on Current Biosafety Management Status in Laboratory Animal Institutions in Hunan Province [J]. Laboratory Animal and Comparative Medicine, 2024, 44(2): 202-208.
[13]	Bing CHEN, Yixing ZOU, Lingyun YAO, Jingdong WANG. Research on Management Policies of Laboratory Animals in Sichuan Province [J]. Laboratory Animal and Comparative Medicine, 2024, 44(2): 209-213.
[14]	Yong ZHAO. Evolution and Prospects of Laboratory Animal Management: A Case Study of Shanghai's Development in the Past Decade [J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 492-503.
[15]	Lianxiang GUO. Revision of Standards for Microbiological and Parasitological Grades in Laboratory Animals and Its Comparison to Foreign Standards [J]. Laboratory Animal and Comparative Medicine, 2023, 43(4): 339-346.