Investigation and Discussion on the Standardization Work of Feeds for Laboratory Animals

doi:10.12300/j.issn.1674-5817.2022.019

Abstract

Abstract:

Standardization of laboratory animals is the basis for obtaining accurate and stable experimental data, drawing objective and reliable experimental conclusions. The standardization of laboratory animal feeds is an integral part of laboratory animal standardization and an important support to realize laboratory animal standardization. In this paper, we compared the historical process of laboratory animal feeds standardization at home and abroad, outlined the key problems existing in the current domestic work, and put forward targeted countermeasures in order to provide references for the standardization of laboratory animal feeds in China.

Key words: Laboratory animal, Feeds, Standardization

CLC Number:

Q95-33

Jianbo LUO,Junhui LI,Jia ZHOU,et al. Investigation and Discussion on the Standardization Work of Feeds for Laboratory Animals[J]. Laboratory Animal and Comparative Medicine, 2022, 42(5): 458-465. DOI: 10.12300/j.issn.1674-5817.2022.019.

Figures/Tables 1

References 31

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营养成分 Nutrient	需要量（每千克饲料含量）/g Requirements (content in 1 kg feeds )/g
营养成分 Nutrient	维持阶段 Maintenance stage	生长阶段 Growth stage	繁殖阶段（雌性） Reproductive stage (Female)
脂肪 Fat	50.0	50.0	50.0
亚油酸（n-6) Linoleic acid	-	6.0	3.0
蛋白质 Protein	50.0	150.0	150.0
氨基酸 Amino acids
精氨酸 Arginine	-	4.3	4.3
苯丙氨酸+酪氨酸 Phenylalanine + Tyrosine	1.9	10.2	10.2
组氨酸 Histidine	0.8	2.8	2.8
赖氨酸 Lysine	1.1	9.2	9.2
异亮氨酸 Isoleucine	3.1	6.2	6.2
亮氨酸 Leucine	1.8	10.7	10.7
蛋氨酸+半胱氨酸 Methionine + Cystine	2.3	9.8	9.8
苏氨酸 Threonine	1.8	6.2	6.2
色氨酸 Tryptophan	0.5	2.0	2.0
缬氨酸 Valine	2.3	7.4	7.4
矿物质 Mineral
钙 Calcium	5.0	5.0	6.3
氯化物 Chloride	0.5	0.5	0.5
镁 Magnesium	0.5	0.5	0.6
磷 Phosphorus	3.0	3.0	3.7
钾 Potassium	3.6	3.6	3.6
钠 Sodium	0.5	0.5	0.5
铜 Copper	5.0×10^-3	5.0×10^-3	8.0×10^-3
铁 Iron	3.5×10^-2	3.5×10^-2	7.5×10^-2
锰 Manganese	1.0×10^-2	1.0×10^-2	1.0×10^-2
锌 Zinc	1.2×10^-2	1.2×10^-2	2.5×10^-2
碘 Iodine	1.5×10^-4	1.5×10^-4	1.5×10^-4
钼 Molybdenum	1.5×10^-4	1.5×10^-4	1.5×10^-4
硒 Selenium	1.5×10^-4	1.5×10^-4	4.0×10^-4
维生素 Vitamin
维生素A Retinol	7.0×10^-4	7.0×10^-4	7.0×10^-4
维生素D Cholecalciferol	2.5×10^-5	2.5×10^-5	2.5×10^-5
维生素E RRR-α-tocopherol	1.8×10^-2	1.8×10^-2	1.8×10^-2
维生素K Phylloquinone	1.0×10^-3	1.0×10^-3	1.0×10^-3
生物素 Biotin	2.0×10^-4	2.0×10^-4	2.0×10^-4
胆碱 Choline	0.75	0.75	0.75
叶酸 Folic acid	1.0×10^-3	1.0×10^-3	1.0×10^-3
烟酸 Niacin	1.5×10^-2	1.5×10^-2	1.5×10^-2
泛酸 Pantothenate	1.0×10^-2	1.0×10^-2	1.0×10^-2
核黄素 Riboflavin	3.0×10^-3	3.0×10^-3	4.0×10^-3
硫胺素 Thiamin	4.0×10^-3	4.0×10^-3	4.0×10^-3
维生素B6 Pyridoxine	6.0×10^-3	6.0×10^-3	6.0×10^-3
维生素B12 Cobalamine	5.0×10^-5	5.0×10^-5	5.0×10^-5

营养成分 Nutrient	需要量（每千克饲料含量）/g Requirements (content in 1 kg feeds )/g
营养成分 Nutrient	维持阶段 Maintenance stage	生长阶段 Growth stage	繁殖阶段（雌性） Reproductive stage (Female)
脂肪 Fat	50.0	50.0	50.0
亚油酸（n-6) Linoleic acid	-	6.0	3.0
蛋白质 Protein	50.0	150.0	150.0
氨基酸 Amino acids
精氨酸 Arginine	-	4.3	4.3
苯丙氨酸+酪氨酸 Phenylalanine + Tyrosine	1.9	10.2	10.2
组氨酸 Histidine	0.8	2.8	2.8
赖氨酸 Lysine	1.1	9.2	9.2
异亮氨酸 Isoleucine	3.1	6.2	6.2
亮氨酸 Leucine	1.8	10.7	10.7
蛋氨酸+半胱氨酸 Methionine + Cystine	2.3	9.8	9.8
苏氨酸 Threonine	1.8	6.2	6.2
色氨酸 Tryptophan	0.5	2.0	2.0
缬氨酸 Valine	2.3	7.4	7.4
矿物质 Mineral
钙 Calcium	5.0	5.0	6.3
氯化物 Chloride	0.5	0.5	0.5
镁 Magnesium	0.5	0.5	0.6
磷 Phosphorus	3.0	3.0	3.7
钾 Potassium	3.6	3.6	3.6
钠 Sodium	0.5	0.5	0.5
铜 Copper	5.0×10^-3	5.0×10^-3	8.0×10^-3
铁 Iron	3.5×10^-2	3.5×10^-2	7.5×10^-2
锰 Manganese	1.0×10^-2	1.0×10^-2	1.0×10^-2
锌 Zinc	1.2×10^-2	1.2×10^-2	2.5×10^-2
碘 Iodine	1.5×10^-4	1.5×10^-4	1.5×10^-4
钼 Molybdenum	1.5×10^-4	1.5×10^-4	1.5×10^-4
硒 Selenium	1.5×10^-4	1.5×10^-4	4.0×10^-4
维生素 Vitamin
维生素A Retinol	7.0×10^-4	7.0×10^-4	7.0×10^-4
维生素D Cholecalciferol	2.5×10^-5	2.5×10^-5	2.5×10^-5
维生素E RRR-α-tocopherol	1.8×10^-2	1.8×10^-2	1.8×10^-2
维生素K Phylloquinone	1.0×10^-3	1.0×10^-3	1.0×10^-3
生物素 Biotin	2.0×10^-4	2.0×10^-4	2.0×10^-4
胆碱 Choline	0.75	0.75	0.75
叶酸 Folic acid	1.0×10^-3	1.0×10^-3	1.0×10^-3
烟酸 Niacin	1.5×10^-2	1.5×10^-2	1.5×10^-2
泛酸 Pantothenate	1.0×10^-2	1.0×10^-2	1.0×10^-2
核黄素 Riboflavin	3.0×10^-3	3.0×10^-3	4.0×10^-3
硫胺素 Thiamin	4.0×10^-3	4.0×10^-3	4.0×10^-3
维生素B6 Pyridoxine	6.0×10^-3	6.0×10^-3	6.0×10^-3
维生素B12 Cobalamine	5.0×10^-5	5.0×10^-5	5.0×10^-5

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