Abstract: Objective To determine and comparative analysis of hemorheological parameters and blood coagulation function in WHBE rabbits，Japanese White rabbits and New Zealand White rabbits，and further to reveal on hemorrheological and blood coagualtion system characteristics of WHBE rabbits.Methods Fourty in each of WHBE rabbits，Japanese White rabbits and New Zealand White rabbits，half male and female，the anticoagulant blood samples from the central artery of ear，and then hemorrheological parameters and blood coagulation function were determined by automatic hemorheology analyzer and CA-500 automatic blood coagulation analyzer，respectively.Results（1）Gender factor has significant influences on hematocrit，the erythrocyte sedimentation rate，K value of erythrocyte sedimentation rate equation and erythrocyte accounts in WHBE rabbits（〈i>P＜0.05，P＜0.01），but has no significant influence to blood coagulation of WHBE rabbits（尸>0.05）；（2）Compared with WHBE rabbits，the hemorheological parameters of WHBE rabbits have no significant difference to Japanese White rabbits（尸>0.05），but PT，PT/R，PTINR of female WHBE rabbits were obvious higher than those of female Japanese White rabbits（P＜0.05），and PT%was lower than that of female Japanese White rabbits（P＜0.05）；while whole blood viscosity at low shear rate，Fbg and TT of male WHBE rabbits were higher than those of male New Zealand White rabbits（P＜0.05），hematocrit was obviously lower in WHBE rabbit than those of New Zealand White rabbits（P＜0.05），moreover，the whole blood viscosity，capillary plasma viscosity，blood reduced viscosity at low and high shear rate，erythrocyte deformation index，erythrocyte electrophoresis index，casson viscosity and PT%were higher in female WHBE rabbits than those of female new Zealand White rabbits（P＜0.05，P＜0.01），while hermatocrit，K value of erythrocyte sedimentation rate equation，PT，PT/R and PTINR was significant lower than those of female New Zealand White rabbits（P