Comparison on Organ Parameter, Blood Parameter, Heart Rate and Ventricular Pressure between Male and Femele New Zealand White Rabbit

doi:10.3969/j.issn.1674-5817.2016.01.006

Abstract

Abstract: Objective To determine and compare the parameters of organ and blood, heart rate and ventricular pressure in New Zealand white rabbit. Methods A total of 60 New Zealand white rabbits about 70-80 days old were fed for a week. Weight of rabbit and main organ, blood physiological and biochemical index and blood gas, ventricular pressure and heart rate were determined on respiratory support condition. Result The thymus gland and lung organ coefficient differences were significant between male and female rabbits (P<0.05 or P<0.01). Percentage of eosinophils, neutrophils, mononuclear cell and lymphocyte, neutrophils, mononuclear cell, mean corpuscular volume, average amount of hemoglobin, serum albumin /globulin, blood glucose, complement C3, glutamyl- transpeptidase, value of pH, temperature correction pH, oxygen saturation differences were significant (P<0.05 or P<0.01). The left and right ventricular diastolic blood pressure differences were also significant(P<0.05). Conclusion Some of the organ coefficient, blood physiological and biochemical index, blood gas analysis and ventricular pressure exist significant difference between male and female New Zealand white rabbit, it should be paid attention in related research.

Key words: New Zealand white rabbit, Organ parameter, Blood parameter, Ventricular pressure

CLC Number:

Q95-33

ZHANG Xiao-yu, ZHANG Xiu-yan, ZHAN Chun-lie. Comparison on Organ Parameter, Blood Parameter, Heart Rate and Ventricular Pressure between Male and Femele New Zealand White Rabbit[J]. Laboratory Animal and Comparative Medicine, 2016, 36(1): 32-36.

References

[1] 袁进, 顾为望, 张嘉宁, 等. SPF级和普通级新西兰兔主要脏器系数的比较[J]. 中国比较医学杂志, 2006, 16(12):749-751.
[2] 李英. SPF级新西兰实验兔生物学特性的研究[D]. 广州: 第一军医大学, 2004:28-30.
[3] 恽时锋. 实验型封闭群新西兰兔与应用有关的生物学特性研究[D]. 南京: 南京农业大学, 2003:48-45.
[4] 李增强, 孙淑华, 孟金萍, 等. 无菌兔、SPF兔和普通兔脏器系数的比较[J]. 中国比较医学杂志, 2009, 19(1):37-40.
[5] 张修彦, 詹纯列, 肖育华, 等. SPF级Balb/c小鼠脏器质量、脏器系数、血常规、血生化指标的测定与比较[J]. 中国组织工程研究与临床康复, 2011, 15(41):7734-7737.
[6] 田小芸, 赵志刚, 恽时锋, 等. 先天性白内障大鼠主要脏器重量与脏器系数[J]. 实验动物与比较医学, 2014, 34(5):386-388.
[7] 吴旭颖, 田玉书, 吴金峰, 等. BALB/cA-nu小鼠主要脏器参数、血生理生化指标和免疫细胞的测定[J]. 中国比较医学杂志, 2014, 24(5):41-46.
[8] 韩芬茹. 四种实验动物脏器质量系数的测定[J]. 畜牧兽医杂志, 2006, 4(25):1-3.
[9] 田小芸, 尤金炜, 董敏, 等. 先天性白内障大鼠血液生化及血液流变学分析[J]. 中国比较医学杂志, 2014, 24(3):20-24.
[10] 丁雷. 新西兰兔血液学参数的研究[D]. 哈尔滨: 东北林业大学, 2010:19-31.
[11] 岳秉飞, 程水生, 杨果杰, 等. 不同周龄大耳白兔血液生理生化指标的测定[J]. 中国兽药杂志, 2000, 35(3):17-21.
[12] 赵晓红. 血液标本存放时间对生化检验结果的影响研究[J]. 中国保健营养, 2013, (4):2127.
[13] 柯斌, 秦鉴, 张俊杰. 短期禁食对大鼠生理生化指标的影响[J]. 时珍国医国药, 2011(22):2778-2780.
[14] 郑凤娇, 傅泳航, 刘光泽, 等. HBV转基因小鼠血液生理生化指标检测分析[J]. 解放军医学杂志, 2011, 36(9):970-972.
[15] 王新. 阿托伐他汀对兔肺动脉高压的作用及对白介素-6水平的影响[D]. 石家庄: 河北医科大学, 2012:13-20.
[16] 董浩然. 新西兰兔心衰心气虚证模型的建立及其基因芯片数据分析[D]. 广州: 广州中医药大学, 2013:18-20.