Abstract: Objective Construct nonlinear equation between emotion and micro-index using female experimental macaque to provide subject supporting for revealing the famous TCM theory of “liver controlling dispersion”. Methods Adopt the project described by Carol A.Shively to select different status macaque enter experiment,use Emotional Evaluation Scale about Female Experiment Macaque to score macaques’ emotion，collect blood and urine to test transmitter and hormone content in vivo, and construct nonlinear equation by using mathematics modeling method. Results The liver-qi invasion macaques had a atypia negative correlation between 5-HT content and indignation emotion,while with the increasing of P content，the score of indignation factor descended rapidly in protophase and slowly in anaphase applying Scale method to investigate the relationship of expression&behaviour and transmitter&hormone level in vivo on macaques model. Conclusion There is a very complicated relationship between emotion and micro-index in vivo, and the emotion fluctuation maybe related to P、 PRL、5-HT content in vivo closely.

Key words: PMS Liver-qi Invasion, Liver-qi Depression, Scale, Nonlinear equation