Laboratory Animal and Comparative Medicine ›› 2023, Vol. 43 ›› Issue (1): 67-72.DOI: 10.12300/j.issn.1674-5817.2022.118

Special Issue: 实验动物资源开发与利用

• Development and Utilization of Laboratory Animal Resources • Previous Articles     Next Articles

A Preliminary Study on the Domestication and Breeding Methods of Experimental Cats

Yongping HE(), Meixian XIE, Zhihui PANG, Qingxiu LI, Huahong HE, Namin ZHANG, Wei LI()   

  1. Guangzhou Institute for Drug Control, Guangzhou 510160, China
  • Received:2022-08-03 Revised:2022-10-26 Online:2023-02-25 Published:2023-03-09
  • Contact: Wei LI

Abstract:

Objective Focused on the laboratory animal domestication and breeding of domestic cats, to explore the feeding management methods and breeding techniques of experimental cats. Methods Seven Chinese garden cats from three litters were introduced from the rural suburbs of Guangzhou, and a breeding seed colony was established. The cats were domesticated in captivity, bred, closed breeding and transmission according to the feeding and management methods of laboratory animal. The population reproduction, the number of pregnancies per year, the litter season, the birth and weaning quality of the cats, and the survival rate of weaning were statistically collected. Results The young breeding cats were able to adapt to the cage feeding management. In the transmission breeding and the expanded breeding colony, the number of female cats pregnant with one, two or three litters a year accounted for 63.2%, 26.3% and 10.5%, respectively. The proportions of litters born from the 1st to the 4th quarters were 20.7%, 20.7%, 27.6%, and 31.0%. A total of 29 pregnancies and 101 kittens were got from 19 female cats, with an average of (3.5±1.33) kittens per litter. The birth weights of female and male cats were (89.31±13.69) g and (93.47±15.12) g, respectively. Sixty-seven kittens survived from weaning. The average survival rate was 60.86%, and the weaning weights of female and male cats were (361.62±82.77) g and (376.0±91.71) g, respectively. Conclusion Domestic Chinese garden cats can adapt to laboratory animal feeding and breeding rules, and have strong fertility. They can normally pregnant and breeding throughout the year. The kittens grow to 5-6 months of age can meet the weight requirements for the examination of pharmaceutical hypotensive substances, and can be used as experimental cats for pharmaceutical examination with clear origin.

Key words: Chinese garden cats, Laboratory animal domestication, Reproductive performance, Litter size, Weaning survival rate

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