Abstract: Objective To discuss the gain value of SPECT/CT bone fusion imaging and bone planar scintigraphy in the diagnosis of stress fracture. Methods Twelve male New Zealand White rabbits were randomly divided into two groups, including 8 in the experimental group and 4 in the control. In the experimental group, 8 rabbits were given electronic stimulation regularly to let it jump in a special device for five weeks. Meanwhile, the control group was allowed for free activities. All of them had undergone both ⁹⁹Tc^m-MDP bone planar imaging and SPECT/CT bone fusion imaging. All of bone planar images, bone SPECT images and SPECT/CT fusion images were diagnosis by 2 nuclear medicine physicians in double-blind method. All results were confirmed by pathological examination. Results The sensitivity, specificity and accuracy of bone planar imaging diagnosis of stress fracture were 31.25％(5/16)、87.50％(7/8) and 50.00％(12/24), respectively; the sensitivity, specificity and accuracy of SPECT/CT bone fusion imaging in the diagnosis of stress fracture were 75.00％(12/16)、87.50％(7/8) and 79.17％(19/24). Conclusions SPECT/CT bone fusion imaging has a higher sensitivity and specificity in the diagnosis of stress fracture, and it can further improve the diagnostic accuracy.

Key words: Stress fracture, Bone scintigraphy, SPECT/CT, MDP