Laboratory Animal and Comparative Medicine ›› 2013, Vol. 33 ›› Issue (1): 74-78.DOI: 10.3969/j.issn.1674-5817.2013.01.017

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Research Advance on Parkinson’s Disease Cell Model

FAN Zhen-qun1, LIU Shu-min1, ZHOU Shi-hui1, WANG Ke-xin1   

  1. 1. Institute of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040,China
  • Received:2012-04-19 Online:2013-02-25 Published:2013-02-25

Abstract: Parkinson’s disease, which serious endangers the health of middle- aged and elderly pepole, has attracted more and more attention in these years. In the study of Parkinson‘s disease, the in vivo experiments will spend more time and money. Because of that, a lot of in vitro models have been used to reflect the pathological changes and the efficacy of new drug. Many reagents have their own specialities, and different cell lines also have their own characters, and their cell model will finally influenced the research outcome.

Key words: Parkinson's disease, Cell model, MPP+, Rotenone, SH-SY5Y

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