Abstract: Objective To design the evaluation index system of preparation efficacy on sodium-selenite-induced cataract in neonate rats，on the basis of the animal models’ establishment，combined with the establishment principle of evaluation index system and the preparation principle of animal models of human disease. Methods Through literature research, 26 indicators for evaluating the system for sodium-selenite-induced cataract in neonate rats were collected . According to the research report and the effects of various factors on the preparation of sodium-selenite-induced cataract in neonate rats, coupled with Delphi method and AHP (analytic hierarchy process), we designed the preparation effect evaluation index system and established the animal model. Results Through the evidence, the evaluation index system was confirmed as a good system. Conclution The evaluation index system set up in this study was a clear, simple and easy-to-use system.

Key words: Sodium-selenite-induced cataract, Animal model, Delphi method, AHP, Evaluation index system