Primary Emerging and Prevalent Infectious Agents in Rodents

doi:10.3969/j.issn.1674-5817.2011.05.020

Abstract

Abstract: With the rapid development of Bio-pharmaceutical industry and the broader and deeper international intercommunion in laboratory animal, there is a new feature expressed in disease prevalence in lab animals, especially in rats and mice. One hand, some emerging infectious agents are becoming more prevalent in lab animal colonies. On the other hand, a few traditional infectious agents which are required to be monitored routinely from national standard still keep high infection rates in rodents. Many of these infections may result in significant changes in immune function, the physiology and biochemistry of animals, and animal reproduction, even presence of clinical and pathological signs in animals. These alterations are serous variables that can have a devastating effect on animal colonies and research results. This article provides an overview of the prevalence, discovery, diagnosis, and research impact of the primary emerging and prevalent infectious agents in other countries recently in laboratory rodents. Hopefully, this article could be useful information to laboratory animal veterinarian or laboratory animal facility management in China.

Key words: Rodents, Emerging and Prevalent infectious agents

CLC Number:

Q95-33

LIU Ji-hong, SHEN Zhi, WANG Jian-fei. Primary Emerging and Prevalent Infectious Agents in Rodents[J]. Laboratory Animal and Comparative Medicine, 2011, 31(5): 392-398.

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