Laboratory Animal and Comparative Medicine ›› 2023, Vol. 43 ›› Issue (5): 482-491.DOI: 10.12300/j.issn.1674-5817.2023.114
Special Issue: 实验动物资源开发与利用
• Frontier Reviews • Previous Articles Next Articles
Received:
2023-08-10
Revised:
2023-10-02
Online:
2023-10-25
Published:
2023-11-01
Contact:
Jianyun XIE
CLC Number:
Jianyun XIE. Research Progress Report on Microtus fortis as a New Resource of Laboratory Animal[J]. Laboratory Animal and Comparative Medicine, 2023, 43(5): 482-491.
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URL: https://www.slarc.org.cn/dwyx/EN/10.12300/j.issn.1674-5817.2023.114
项目 Items | 洞庭湖种群(n=40) Population of Dongtinghu | 青铜峡种群(n=40) Population of Qingtongxia | ||||
---|---|---|---|---|---|---|
♀ | ♂ | ♀ | ♂ | |||
体质量/g Body mass/g | 53.590±7.360 | 67.836±9.235# | 45.960±4.670 | 65.130±9.690# | ||
心脏/体质量 Heart/body mass | 0.480±0.068 | 0.429±0.052 | 0.413±0.037 | 0.404±0.062 | ||
肺/体质量 Lung/body mass | 0.515±0.071 | 0.434±0.062 | 0.456±0.072 | 0.433±0.063 | ||
肝/体质量 Liver/body mass | 3.825±0.514 | 3.802±0.643 | 3.134±0.004 | 3.177±0.343 | ||
脾/体质量 Spleen/body mass | 0.097±0.031 | 0.071±0.014 | 0.071±0.029 | 0.066±0.022 | ||
左肾/体质量 Left kidney/body mass | 0.479±0.069 | 0.464±0.058 | 0.443±0.037 | 0.466±0.043 | ||
右肾/体质量 Right kidney/body mass | 0.472±0.065 | 0.454±0.058 | 0.442±0.038 | 0.466±0.049 | ||
脑/体质量 Brain/body mass | 1.464±0.162 | 1.190±0.145 | 1.711±0.191 | 1.270±0.179# | ||
左甲状腺/体质量 Left thyroid gland/body mass | 0.005±0.002 | 0.002±0.001# | 0.002±0.001* | 0.002±0.001 | ||
右甲状腺/体质量 Right thyroid gland/body mass | 0.005±0.002 | 0.002±0.001# | 0.002±0.001* | 0.001±0.001 | ||
左肾上腺/体质量 Left adrenal gland/body mass | 0.020±0.007 | 0.008±0.003# | 0.011±0.004* | 0.007±0.003 | ||
右肾上腺/体质量 Right adrenal gland/body mass | 0.019±0.007 | 0.008±0.003# | 0.011±0.004* | 0.007±0.003 | ||
左卵巢/体质量 Left ovary/body mass | 0.014±0.008 | / | 0.005±0.003* | / | ||
右卵巢/体质量 Right ovary/body mass | 0.014±0.008 | / | 0.005±0.003* | / | ||
左睾丸/体质量 Left testicle/body mass | / | 0.484±0.128 | / | 0.327±0.200* | ||
右睾丸/体质量 Right testicle/body mass | / | 0.474±0.128 | / | 0.333±0.200* | ||
胸腺/体质量 Thymus/mass | 0.121±0.047 | 0.194±0.067# | 0.120±0.044 | 0.103±0.037 |
Table 1 Comparison of body mass and organ coefficient between the two populations of reed voles
项目 Items | 洞庭湖种群(n=40) Population of Dongtinghu | 青铜峡种群(n=40) Population of Qingtongxia | ||||
---|---|---|---|---|---|---|
♀ | ♂ | ♀ | ♂ | |||
体质量/g Body mass/g | 53.590±7.360 | 67.836±9.235# | 45.960±4.670 | 65.130±9.690# | ||
心脏/体质量 Heart/body mass | 0.480±0.068 | 0.429±0.052 | 0.413±0.037 | 0.404±0.062 | ||
肺/体质量 Lung/body mass | 0.515±0.071 | 0.434±0.062 | 0.456±0.072 | 0.433±0.063 | ||
肝/体质量 Liver/body mass | 3.825±0.514 | 3.802±0.643 | 3.134±0.004 | 3.177±0.343 | ||
脾/体质量 Spleen/body mass | 0.097±0.031 | 0.071±0.014 | 0.071±0.029 | 0.066±0.022 | ||
左肾/体质量 Left kidney/body mass | 0.479±0.069 | 0.464±0.058 | 0.443±0.037 | 0.466±0.043 | ||
右肾/体质量 Right kidney/body mass | 0.472±0.065 | 0.454±0.058 | 0.442±0.038 | 0.466±0.049 | ||
脑/体质量 Brain/body mass | 1.464±0.162 | 1.190±0.145 | 1.711±0.191 | 1.270±0.179# | ||
左甲状腺/体质量 Left thyroid gland/body mass | 0.005±0.002 | 0.002±0.001# | 0.002±0.001* | 0.002±0.001 | ||
右甲状腺/体质量 Right thyroid gland/body mass | 0.005±0.002 | 0.002±0.001# | 0.002±0.001* | 0.001±0.001 | ||
左肾上腺/体质量 Left adrenal gland/body mass | 0.020±0.007 | 0.008±0.003# | 0.011±0.004* | 0.007±0.003 | ||
右肾上腺/体质量 Right adrenal gland/body mass | 0.019±0.007 | 0.008±0.003# | 0.011±0.004* | 0.007±0.003 | ||
左卵巢/体质量 Left ovary/body mass | 0.014±0.008 | / | 0.005±0.003* | / | ||
右卵巢/体质量 Right ovary/body mass | 0.014±0.008 | / | 0.005±0.003* | / | ||
左睾丸/体质量 Left testicle/body mass | / | 0.484±0.128 | / | 0.327±0.200* | ||
右睾丸/体质量 Right testicle/body mass | / | 0.474±0.128 | / | 0.333±0.200* | ||
胸腺/体质量 Thymus/mass | 0.121±0.047 | 0.194±0.067# | 0.120±0.044 | 0.103±0.037 |
项目 Items | 洞庭湖种群(n=40) Population of Dongtinghu | 青铜峡种群(n=40) Population of Qingtongxia | |||
---|---|---|---|---|---|
♀ | ♂ | ♀ | ♂ | ||
红细胞计数/(1012·L-1) Red blood cell count | 9.41±1.12 | 10.43±0.84 | 10.91±0.82 | 11.18±0.86 | |
血红蛋白ρ/(g·L-1) Hemoglobin | 141.63±16.54 | 162.95±11.24# | 154.58±12.23 | 160.95±12.30 | |
白细胞计数/(109·L-1) White blood cell count | 4.78±1.78 | 8.77±2.77# | 4.03±1.76 | 5.08±1.79*# | |
噬中性粒细胞百分比/% Percentage of phagocytic neutrophils | 30.97±10.75 | 18.40±11.45# | 20.58±7.97* | 26.47±14.56*# | |
淋巴细胞百分比/% Percentage of lymphocytes | 62.76±11.28 | 73.75±12.63# | 73.92±8.73 | 65.21±14.48 | |
嗜酸性粒细胞百分比/% Percentage of eosinophils | 4.55±4.13 | 6.62±4.78# | 4.89±3.07 | 6.93±4.85# | |
嗜碱性粒细胞百分比/% Percentage of basophils | 0 | 0.03±0.08 | 0 | 0 | |
单核细胞百分比/% Percentage of monocytes | 1.74±1.69 | 1.19±1.10 | 0.60±1.07* | 1.39±1.65# | |
血小板计数/(109·L-1) Platelet count | 820.94±259.14 | 782.08±183.05 | 572.13±213.17* | 594.16±194.34* |
Table 2 Comparison of hematological index measurement results between the two populations of reed voles
项目 Items | 洞庭湖种群(n=40) Population of Dongtinghu | 青铜峡种群(n=40) Population of Qingtongxia | |||
---|---|---|---|---|---|
♀ | ♂ | ♀ | ♂ | ||
红细胞计数/(1012·L-1) Red blood cell count | 9.41±1.12 | 10.43±0.84 | 10.91±0.82 | 11.18±0.86 | |
血红蛋白ρ/(g·L-1) Hemoglobin | 141.63±16.54 | 162.95±11.24# | 154.58±12.23 | 160.95±12.30 | |
白细胞计数/(109·L-1) White blood cell count | 4.78±1.78 | 8.77±2.77# | 4.03±1.76 | 5.08±1.79*# | |
噬中性粒细胞百分比/% Percentage of phagocytic neutrophils | 30.97±10.75 | 18.40±11.45# | 20.58±7.97* | 26.47±14.56*# | |
淋巴细胞百分比/% Percentage of lymphocytes | 62.76±11.28 | 73.75±12.63# | 73.92±8.73 | 65.21±14.48 | |
嗜酸性粒细胞百分比/% Percentage of eosinophils | 4.55±4.13 | 6.62±4.78# | 4.89±3.07 | 6.93±4.85# | |
嗜碱性粒细胞百分比/% Percentage of basophils | 0 | 0.03±0.08 | 0 | 0 | |
单核细胞百分比/% Percentage of monocytes | 1.74±1.69 | 1.19±1.10 | 0.60±1.07* | 1.39±1.65# | |
血小板计数/(109·L-1) Platelet count | 820.94±259.14 | 782.08±183.05 | 572.13±213.17* | 594.16±194.34* |
项目 Items | 洞庭湖种群田鼠(n=40) Population of Dongtinghu | 青铜峡种群田鼠(n=40) Population of Qingtongxia | |||
---|---|---|---|---|---|
♀ | ♂ | ♀ | ♂ | ||
天门冬氨酸转氨酶z/(U·L-1) Aspartate aminotransferase | 417.36±233.64 | 351.20±226.26# | 226.09±86.23* | 304.50±133.46# | |
谷丙转氨酶z/(U·L-1) Alanine transaminase | 285.57±180.13 | 217.40±146.94# | 134.69±49.60* | 155.90±78.57* | |
碱性磷酸酶z/(U·L-1) Alkaline phosphatase | 353.31±149.88 | 253.90±64.11# | 392.53±82.90 | 388.20±81.57* | |
乳酸脱氢酶z/(U·L-1) Lactate dehydrogenase | 1 036.62±294.83 | 764.40±458.96# | 373.64±281.42* | 536.30±345.63*# | |
肌苷c/(μmol·L-1) Inosine | 11.67±3.51 | 10.60±3.49 | 9.33±2.91* | 11.50±3.33# | |
尿素c/(mmol·L-1) Urea | 9.39±2.08 | 8.90±1.62 | 9.48±2.63 | 8.70±2.45 | |
总胆固醇c/(mmol·L-1) Total cholesterol | 2.67±0.69 | 2.20±0.49 | 3.80±0.71* | 3.20±0.76* | |
血清总蛋白ρ/(g·L-1) Total serum protein | 64.55±4.73 | 64.40±3.89 | 59.28±3.74 | 61.00±4.98 | |
白蛋白ρ/(g·L-1) Albumin | 40.82±2.76 | 42.20±2.45 | 38.65±2.99 | 39.40±3.07 | |
甘油三酯/(mmol·L-1) Triglyceride | 1.62±1.09 | 1.30±0.68 | 1.81±1.13 | 1.60±0.77 | |
血糖c/(mmol·L-1) Blood sugar | 2.25±0.70 | 2.60±0.69 | 2.39±0.86 | 2.10±0.79 | |
高密度脂蛋白c/(mmol·L-1) High density lipoprotein | 1.69±0.41 | 1.20±0.22# | 2.00±0.23 | 1.60±0.33 | |
低密度脂蛋白c/(mmol·L-1) Low density lipoprotein | 0.65±0.29 | 0.40±0.22# | 0.85±0.48* | 0.80±0.39* | |
胆碱酯酶z/(U·L-1) Cholinesterase | 7 631.09±1 338.15 | 8 053.00±2 329.15 | 8 626.18±2 049.57 | 9 249.70±2 790.19 | |
尿比重 Urine specific gravity | 1.010 1 ±0.007 7 | 1.018 3 ±0.012 9 | 1.021 7±0.014 5 | 1.029 1±0.014 8 |
Table 3 Comparison of biochemical index measurement results between the two populations of reed voles
项目 Items | 洞庭湖种群田鼠(n=40) Population of Dongtinghu | 青铜峡种群田鼠(n=40) Population of Qingtongxia | |||
---|---|---|---|---|---|
♀ | ♂ | ♀ | ♂ | ||
天门冬氨酸转氨酶z/(U·L-1) Aspartate aminotransferase | 417.36±233.64 | 351.20±226.26# | 226.09±86.23* | 304.50±133.46# | |
谷丙转氨酶z/(U·L-1) Alanine transaminase | 285.57±180.13 | 217.40±146.94# | 134.69±49.60* | 155.90±78.57* | |
碱性磷酸酶z/(U·L-1) Alkaline phosphatase | 353.31±149.88 | 253.90±64.11# | 392.53±82.90 | 388.20±81.57* | |
乳酸脱氢酶z/(U·L-1) Lactate dehydrogenase | 1 036.62±294.83 | 764.40±458.96# | 373.64±281.42* | 536.30±345.63*# | |
肌苷c/(μmol·L-1) Inosine | 11.67±3.51 | 10.60±3.49 | 9.33±2.91* | 11.50±3.33# | |
尿素c/(mmol·L-1) Urea | 9.39±2.08 | 8.90±1.62 | 9.48±2.63 | 8.70±2.45 | |
总胆固醇c/(mmol·L-1) Total cholesterol | 2.67±0.69 | 2.20±0.49 | 3.80±0.71* | 3.20±0.76* | |
血清总蛋白ρ/(g·L-1) Total serum protein | 64.55±4.73 | 64.40±3.89 | 59.28±3.74 | 61.00±4.98 | |
白蛋白ρ/(g·L-1) Albumin | 40.82±2.76 | 42.20±2.45 | 38.65±2.99 | 39.40±3.07 | |
甘油三酯/(mmol·L-1) Triglyceride | 1.62±1.09 | 1.30±0.68 | 1.81±1.13 | 1.60±0.77 | |
血糖c/(mmol·L-1) Blood sugar | 2.25±0.70 | 2.60±0.69 | 2.39±0.86 | 2.10±0.79 | |
高密度脂蛋白c/(mmol·L-1) High density lipoprotein | 1.69±0.41 | 1.20±0.22# | 2.00±0.23 | 1.60±0.33 | |
低密度脂蛋白c/(mmol·L-1) Low density lipoprotein | 0.65±0.29 | 0.40±0.22# | 0.85±0.48* | 0.80±0.39* | |
胆碱酯酶z/(U·L-1) Cholinesterase | 7 631.09±1 338.15 | 8 053.00±2 329.15 | 8 626.18±2 049.57 | 9 249.70±2 790.19 | |
尿比重 Urine specific gravity | 1.010 1 ±0.007 7 | 1.018 3 ±0.012 9 | 1.021 7±0.014 5 | 1.029 1±0.014 8 |
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[1] | GAO Cheng-1, SHEN Zhi-Min-1, LIU Xiong-Wei-1, LU Guo-Ping-1, SHAO Wei-Juan-1, WANG Sheng-Chang-1, BAI Xiong-2. Detection of Microorganisms and Parasites in Field Vole (Microtus fortis)from Different Rigions in China [J]. , 2000, 20(1): 22-25. |
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