Abstract: Objective To detect and compare the differences in main organ weight and coefficient between conventional and clean Cricetulus griseus. Methods Forty conventional and clean Cricetulus griseus were dissected respectively. Weight of tissues and organs was measured with electronic balance to detect indices of 12 organs, and the organ coefficient were calculated. Result Compared with the conventional and clean male Cricetulus griseus, there was statistical significance in weight of heart, liver and epididymis (P<0.01), and in visceral coefficient of brain and kidney (P<0.01). Compared with the conventional and clean female Cricetulus griseus ,showed statistical significances in weight of heart and renal coefficient (P<0.05). In conventional Cricetulus griseus, spleen coefficient was different between male and female (P<0.05). In clean Cricetulus griseus, there was statistical significance in heart coefficient between male and female (P<0.01). Conclusions There are obvious differences in weight and coefficient of organs between clean and conventional Cricetulus griseus.

Key words: Cricetulus griseus, Conventional, Clean, Weight, Organ, Coefficient