Catheterization Caused Congestive Heart Failure Rabbit Model of Heart Qi deficiency

doi:10.3969/j.issn.1674-5817.2012.03.006

Abstract

Abstract: Objective To construct congestive heart failure rabbit model of heart Qi deficiency caused by catheterization. Methods Construct cardiac hyper-volume overload, rabbit heart failure model was caused by catheterization.Fifteen and 30 days after modeling, the general status, feed consumption index, body weight index, heart rate, respiration and ECG were observed and measured. Results Compared with the normal control group, SBP, DBP, LVSP and other hemodynamic index decreased significantly. After 15 and 30 days of modeling, the activity of model's rabbit was significantly reduced, the apathetic, efforts of resisting grab were reduced, feed consumption and body weight indices were decreased, breathing and heart rate were increased significantly, abnormal Q wave was appeared, and ST wave segment was elevated. Conclusion The heart rate, respiration, ECG, body weight and feed consumption index and other indicators can qualitatively and quantitatively reflect the heart failure model of heart qi deficiency.

Key words: Congestive heart failure, Heart qi deficiency, Rabbit, Model

CLC Number:

Q95-33

WANG Xiao,DONG Hao-ran,LIN Chuan-quan,et al. Catheterization Caused Congestive Heart Failure Rabbit Model of Heart Qi deficiency[J]. Laboratory Animal and Comparative Medicine, 2012, 32(3): 199-202. DOI: 10.3969/j.issn.1674-5817.2012.03.006.

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Catheterization Caused Congestive Heart Failure Rabbit Model of Heart Qi deficiency

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