Investigation on Electrocardiogram of Bama Minipigs by Telemetry

doi:10.3969/j.issn.1674-5817.2017.05.013

Laboratory Animal and Comparative Medicine ›› 2017, Vol. 37 ›› Issue (5): 410-413.DOI: 10.3969/j.issn.1674-5817.2017.05.013

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Investigation on Electrocardiogram of Bama Minipigs by Telemetry

YANG Li-chang¹, ZHOU Wen-bing¹, DING Jun¹, ZHOU Xin-chu², XIE Dong¹, YANG Wei-min¹

1. Shanghai Chempartner Co. Ltd, Shanghai 201203, China;
2. School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai 200240, China

Received:2017-04-28 Online:2017-10-25 Published:2017-10-25

Abstract

Abstract: Objective To collect and analyze electrocardiogram (ECG) data by ECG telemetry system in Bama minipigs reared in Shanghai. Method Twenty male Bama minipigs aged at 4 to 8 months were randomly selected from the healthy colony of Shanghai huaxin special breeding farm. ECG data were recorded by Beijing softron telemetry system and analyzed by the analysis system-SP2006. Result In Bama minipigs, heart rate was (82±11) beat/min, PR interval was (97±11) ms, QRS and QT intervals were (42±4) ms and (293±15) ms, QTc was 271±19, left axis deviation and T-wave inversion happened in colony. Conclusion The ECG telemetry system can be used to monitor ECG data in free moving minipigs, and the ECG data of Bama minipigs can be used as baseline for preclinical studies including, pharmacokinetics, pharmacodynamics, pharmacology and toxicity studies.

Key words: Bama minipigs, Electrocardiogram (ECG), Telemetry technology

CLC Number:

Q95-33

YANG Li-chang, ZHOU Wen-bing, DING Jun, ZHOU Xin-chu, XIE Dong, YANG Wei-min. Investigation on Electrocardiogram of Bama Minipigs by Telemetry[J]. Laboratory Animal and Comparative Medicine, 2017, 37(5): 410-413.

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Investigation on Electrocardiogram of Bama Minipigs by Telemetry

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