Progress on Development and Application of BALB/c Nude Mouse with GFP

doi:10.3969/j.issn.1674-5817.2016.02.016

Abstract

Abstract: It reported here that the development and application of the transgenic green fluorescent protein (GFP) nude mouse with ubiquitous GFP expression. BALB/c nude mouse with GFP were bred for cancer research initially, in which were deficient in T lymphocytes. In the last decades, researchers had studied vastly and deeply the biological characteristics and application of BALB/c nude mouse with GFP. The application of GFP nude mouse model should greatly expanded our knowledge in science research.

Key words: Green fluorescent protein (GFP), Nude mouse, Immunologic characteristics, Tumor models

CLC Number:

Q95-33

FANG Tian, YUN Shi-feng. Progress on Development and Application of BALB/c Nude Mouse with GFP[J]. Laboratory Animal and Comparative Medicine, 2016, 36(2): 152-156.

References

[1] Shimomura O, Johnson FH, Saiga Y.Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea[J]. Cell Comp Physiol,1962, 59:223-239.
[2] Santerre Henriksen AL, Even S, et al.Study of the glucoamylase promoter in Aspergillus niger using green fluorescent protein[J]. Microbiology, 1999, 145(3):729-734.
[3] Soboleski MR, Oaks J, Halford WP.Green fluorescent protein is a quantitative reporter of gene expression in individual eukaryotic cells[J]. FASEB J, 2005, 19(3):440-442.
[4] Davis AR, Meyers K, Wilson JM.High throughput method for creating and screening recombinant adenoviruses[J]. Gene Ther, 1998, 5(8):1148-1152.
[5] Dundr M, McNally JG, Cohen J, et al. Quantitation of GFP fusion proteins in single living cells[J]. Struct Biol, 2002, 140(1-3):92-99.
[6] Iyer S, Arindkar S, Mishra A, et al.Development and evaluation of transgenic nude mice expressing ubiquitous green fluorescent protein[J]. Mol Imaging Biol, 2015, 17(4): 471-478.
[7] Ikawa M, Kominami K, Yoshimura Y, et al.Green fluorescent protein as a marker in transgenic mice[J]. Dev Growth Differ, 1995, 37:455-459.
[8] Yang M, Reynoso J, Jiang P, et al.Transgenic nude mouse with ubiquitous green fluorescent protein expression as a host for human tumors[J]. Cancer Res, 2004, 64(23):8651-8656.
[9] Yang M, Reynoso J, Bouvet M, et al.A transgenic red fluorescent protein-expressing nude mouse for color-coded imaging of the tumor microenvironment[J]. Cell Biochem, 2009, 106(2):279-284.
[10] Tran Cao HS, Reynoso J, Yang M, et al.Development of the transgenic cyan fluorescent protein (CFP)-expressing nude mouse for“Technicolor” cancer imaging[J]. Cell Biochem, 2009, 107(2):328-334.
[11] Bouvet M, Tsuji K, Yang M, et al.In vivo color-coded imaging of the interaction of colon cancer cells and splenocytes in the formation of liver metastases[J]. Cancer Res, 2006, 66(23):11293-11297.
[12] Suetsugu A, Osawa Y, Nagaki M, et al.Imaging the recruitment of cancer-associated fibroblasts by liver-metastatic colon cancer[J]. Cell Biochem , 2011, 112(3):949-953.
[13] Hoffman RM.Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy[J]. Methods Mol Med, 2005, 111:297-322.
[14] 施新猷, 王四旺, 顾为望, 等. 比较医学总论[M]. 西安: 陕西科学技术出版社, 2003:104-105.
[15] Amoh Y, Yang M, Li L, et al.Nestin-linked green fluorescent protein transgenic nude mouse for imaging human tumor angiogenesis[J]. Cancer Res, 2005, 65(12):5352-7.
[16] Miretti S, Roato I, Taulli R, et al.A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by luciferase imaging[J]. PLoS One, 2008, 3(3):e1828.
[17] Chalfie M, Tu Y, Euskirchen G, et al.Green fluorescent protein as a marker for gene expression[J]. Science, 1994, 263:802-805.
[18] Gordon JW, Scangos GA, Plotkin DJ, et al.Genetic transformation of mouse embryos by microinjection of purified DNA[J]. Proc Natl Acad Sci USA, 1980, 77(12):7380-7384.
[19] Yang M, Baranov E, Moossa AR, et al.Visualizing gene expression by whole-body fluorescence imaging[J]. Proc Natl Acad Sci U S A, 2000, 97(22):12278-12282.
[20] Takada T, Iida K, Awaji T, et al.Selective production of transgenic mice using green fluorescence protein as a maker[J]. Nat Biotechnol, 1997, 15:458-461.
[21] Sangmi C, Therese A, Kai CS, et al.Analysis of different promoter systems for efficient transgene expression in mouse embryonic stem cell lines[J]. Stem Cell, 2002, 20(2):139-145.
[22] 张立波, 刘彪, 田小芸, 等. 荧光裸小鼠的选育初报[J]. 实验动物与比较医学, 2013, 33(4):306-309.
[23] 尤金炜, 董敏, 刘彪, 等. GFP在绿色荧光裸鼠不同组织中的表达及分析[J]. 中国实验动物学报, 2014, 22(5):67-70.
[24] 恽时锋, 朱虹. 在生命科学中影响动物实验结果的多因素分析[J]. 医学研究生学报, 2003, 16(5):372-375,378.
[25] 尤金炜, 张立波, 方天, 等. 绿色荧光裸鼠血液生理生化指标检测分析[J]. 中国比较医学杂志, 2013, 23(9):62-69.
[26] 方天, 尤金炜, 张立波, 等. BALB/c荧光裸鼠脾脏组织学的观察[J]. 中国比较医学杂志, 2012, 22(12):6-9.
[27] 贺晓玉, 何君, 徐艳峰, 等. 绿色荧光蛋白转基因小鼠的生理生化常数[J]. 中国实验动物学报, 2011, 19(2):146-149.
[28] 田小芸, 恽时锋, 胡玉红, 等. 转基因EGFP小鼠血液生理生化指标的测定[J]. 实验动物科学, 2008, 25(10):56-58.
[29] 王冬平, 李善如, 张敏, 等. 三种小鼠血液生理生化正常值的测定[J]. 实验动物科学与管理, 2000, 17(2):24-28.
[30] 冯仁田, 潘宏志, 何维, 等. BalB/C小鼠免疫系统结构与功能的增龄性变化[J]. 中华老年医学杂志, 2000, 3:174-178.
[31] 刘中禄, 吕铁钢, 张永亮, 等. 松子壳多糖对小鼠主要免疫细胞功能的影响[J]. 中国比较医学杂志, 2010, 20(10):33-37.
[32] 苗明三, 苗艳艳, 方晓艳, 等. 大枣多糖对大鼠气血双虚模型胸腺、脾脏中组织形态及骨髓象的影响[J]. 中药药理与临床, 2010, 26:42-44.
[33] 苗明三, 孙艳红, 史晶晶, 等. 熟地黄粗多糖对血虚模型小鼠胸腺和脾脏组织形态的影响[J]. 中华中医药杂志, 2007, 22:318-320.
[34] Yang M, Li L, Jiang P, et al.Dual-color fluorescence imaging distinguishes tumor cells from induced host angiogenic vessels and stromal cells[J]. Proc Natl Acad Sci U S A, 2003, 100(24):14259-14262.
[35] Yang M, Jiang P, Hoffman RM, et al.Whole-body subcellular multicolor imaging of tumor-host interaction and drug response in real time[J]. Cancer Res, 2007, 67(11):5195-5200.
[36] Jain RK, Munn LL, Fukumura D.Dissecting tumour pathophysiology using intravital microscopy[J]. Nat Rev Cancer, 2002, 2(4):266-276.
[37] Berndt B, Zanker KS, Dittmar T.Cell fusion is a potent inducer of aneuploidy and drug resistance in tumor cell/normal cell hybrids[J]. Crit Rev Oncog, 2013, 18(1-2):97-113.
[38] 闫寒, 贺小玉, 秦超, 等. 绿色荧光裸鼠的建立和验证[J]. 中国比较医学杂志, 2012, 22(6):62-65.
[39] 代兴亮, 陆朝晖, 王爱东, 等. 双色荧光示踪裸小鼠模型用于脑胶质瘤组织重构的研究[J]. 中华实验外科杂志, 2014, 31(4):774-776.
[40] 胡文娟, 梁磊, 尤金炜, 等. 人结直肠癌细胞绿色荧光蛋白裸鼠移植瘤模型的建立与观察[J]. 中国比较医学杂志, 2014, 24(11):56-60.
[41] HU R, CHENG Y, JING H, et al.Erythropoietin promotes the protective properties of transplanted endothelial progenitor cells against acute lung injury via PI3K/Akt pathway[J]. Shock, 2014, 42(4):327-336.
[42] 张俊华, 郑配国, 马雪涵, 等. 间充质干细胞治疗实验性自身免疫性脑脊髓的疗效和免疫调节机制[J]. 第二军医大学学报, 2015, 36(1):34-38.
[43] Zhao M, Yang M, Li XM, et al.Tumor-targeting bacterial therapy with amino acid auxotrophs of salmonella typhimurium[J]. Anticancer, 2005, 102:755-760.
[44] Hosen N, Shirakata T, Nishida S, et al.The Wilms’ tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis[J]. Leukemia, 2007, 21(8):1783-1791.
[45] Spano D, Zollo M.Tumor microenvironment: a main actor in the metastasis process[J]. Clin Exp Metastasis, 2012, 29(4):381-395.
[46] Briest F, Berudt A, Clement J, et a1. Tumor stroma interactions in tumorigenesis: lessons from stem cell biology[J]. Front Biosci(Elite Ed), 2012, 29(4):1871-1887.