Laboratory Animal and Comparative Medicine ›› 2013, Vol. 33 ›› Issue (3): 243-246.DOI: 10.3969/j.issn.1674-5817.2013.03.017

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Progress on Immune Mechanism of Microtus fortis in Protecting against Schistosoma japonicum Infection

SHAO Guo-yan1,3, XIE Jian-yun2, GAO Cheng2   

  1. 1. Fudan University, Shanghai 201203, China;
    2. Shanghai Laboratory Animal Research Center, Shanghai 201203, China;
    3. Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China
  • Received:2012-08-19 Online:2013-06-25 Published:2013-06-25

Abstract: Microtus fortis (Mf) can be infected with Schistosoma japonicum but without any pathogenic clinical symptom. Mf has a congenital, hereditary resistance mechanism against the infection of Schistosoma japonicum. In recent years, since Mf is acclimated into an experimental animal, the resistance mechanism was deeply investigated by many researchers, this review summarize relative study progress from the aspect of specific and non-specific immunity of Mf.

Key words: Microtus fortis, Schistosoma japonicum, Immune resistance mechanism

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