Abstract:  Many policies, regulations and standards related to laboratory animals have been issued in China with more than 30 years of development. The understanding of the laboratory animal welfare has been deepened in researchers. The operation and management of the Welfare and Ethics Committee have become more and more standardized. The welfare of laboratory animals can be guaranteed with the high quality management of the Welfare and Ethics Committee. Based on the work experiences, searching the literature and peer exchange, the authors described the common problems found in the oversight and ethical review process, and proposed solutions for improving the experimental animal welfare.

Key words: Laboratory animal welfare, Ethical review, Monitoring