Abstract: Objective To obtain the information of AIu I polymorphism distribution of PRLR gene and to study its genetic effect on growth and reproductive performance in Tibet mini-pigs. Methods The litter size and numbers weaning, data of birth weight and weaning weight of piglet from 44 Tibet mini-pig sows were recorded. The AIu I polymorphism of PRLR gene was detected by PCR-RFLP method, and the relationship between the gene polymorphism and the growth and reproductive performance was analyzed by SPSS10.0. Results 3 genotypes of AA、AB、BB were detected in 44 Tibet mini-pigs, the frequency of genotypes was 0.273、0.500、0.227 respectively. Except there was a significant difference in birth weight of latter parity between different genotypes, the other index of growth and reproductive performance between different genolypes had no significance difference. Conclutions There was no significant difference on litter size and numbers of weaning between different genotypes of Tibet mini-pigs.

Key words: PRLR Gene, AIu I Polymorphisms, Tibet mini-pigs, Growth and Reproductive performance