Abstract: To establish the model of restenosis,the metal stent was implanted into the canine femoral artery through the carotid artery.Twelve weeks after the stent implanted,the lumen of canine femoral artery was reduced significantly as a result of smooth muscle cell proliferation and neointima formation. This model is reliable, easier to operate,and resembling the same pathologi-cal changes of clinical restenosis. It is an ideal model for restenosis research.

Key words: Restenosis, Stent, Femoral artery