›› 2000, Vol. 20 ›› Issue (2): 82-85.
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Abstract: The conventional and clean KM,BALB/c and C57BL/6J mice were detected for LCM( lymphocytic choriomeningitis virus), EHFV( epidemic hemorrhagic fever virus),Mouse pox, MPV( mouse hepatitis virus), Sendai virus infetion by using IFA,ELISA,ABC( avidin-biotin-peroxidse complex), and electron microscope before and 15,30,60 days after undergoing animal experiments.The results revealed that 60 days after the animal experiments, ectromelia virus was found in the liver,mesenteric lym-phaden,Payer’s patches, and spleen of seronegative(ELISA,IFA ) KM and BALB/c mice,while in the other groups no ectromelia virus infection were found.The findings suggest that the mice with latent infection of ectromelia virus,despite of sero-negative,would give rise to an outbreak when they were under a long stress of animal experiment ,and the viral antigen detection of Mousepox should be used in routine microbio-logical monitoring.
Key words: Mousepox, Latent infection
LI Jia-Rong-1, QIAN Qin-2, LAI Yong-Lu-2, JIN Feng-2, SONG Xin-Ying-2. Study on Latent Infection of Mousepox[J]. , 2000, 20(2): 82-85.
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https://www.slarc.org.cn/dwyx/EN/Y2000/V20/I2/82