Abstract: The protective effects of Jian-Xue-Bao （made of Spirulina powder） against CC14-induced hepatotoxicity were studied in male SD rats weighed 180 ±13g. The results showed：①in the acute CC1₄-toxicity experiment,Jian-Xue-Bao added to diet for one month could partly protect the rat liver expressed by marked decrease of serum level of ALT，②in the experiment of liver cirrhosis induced by CCl4，Jian-Xue-Bao could partly protect the rat liver expressed by the significant reduction of serum level of laminin and the marked improvement of the pathological change in the pattern of serum amino acids and liver cirrhosis.It is suggested that Jian-Xue-Bao may have the protective effects against CC14-hepatotoxicity.

Key words: Spirulina powder, Protective effect, CCl₄-Hepatotoxicity, Rat