Laboratory Animal and Comparative Medicine ›› 1997, Vol. 17 ›› Issue (4): 207-209.

Previous Articles     Next Articles

Metastatic Models of Human Gastric Carcinoma Established by Orthotopic Implantation of Histologically Intact Specimens in SCID Mice

  

  1. 1.Shanghai Sixth People's Hospital ,Shanghai 200233；2.Shanghai Cancer Institute
  • Received:1997-05-26 Online:1997-01-25 Published:2013-03-19

PDF (PC)

808

Abstract: "To establish the metastatic model of human gastric carcinoma,the histologically intact gastric adenocarcinoma specimens were implanted in the gastric walls of SCID mice. The results showed that the metastasis to the lymph nodes (10/10)，livers (8/10) and lungs (4/10) occured 6 weeks after the implantation. These revealed that the orthotopic implantation of histologically intact carcinoma in SCID mice could give rise to high metastatic rate in short duration. "

Key words: "Gastric adenocarcinoma, Metastatic model, SCID mouse, Orthotopic implantation "